82684-76-2Relevant academic research and scientific papers
Tritylamine (triphenylmethylamine) in organic synthesis; III. The synthesis of 1-aminoalkylphosphonic acids in the reaction of N-(triphenylmethyl) alkanimines with phosphorus trichloride in acetic acid or with phosphonic (phosphorous) acid in acetic anhydride
Goldeman, Waldemar,Soroka, Miroslaw
experimental part, p. 360 - 369 (2011/02/27)
The reaction of phosphorus trichloride in acetic acid or phosphonic (phosphorous) acid in acetic anhydride, with N-(triphenylmethyl)alkanimines gives 1-acetylaminoalkylphosphonic acids 1a-j, which after hydrolysis give 1-aminoalkylphosphonic acids 2a-j in good yields. ARKAT USA, Inc.
1-(N-acylamino)alkanephosphonates. Part IV. N-acylation of 1-aminoalkanephosphonic acids
Kudzin,Depczynski,Andrijewski,Drabowicz,Luczak
, p. 499 - 513 (2007/10/03)
Practical general procedures of N-acylation of 1-aminoalkanephosphonic acids, including N-acetylation, N-benzoylation and N-pivaloylation of the representative aminophosphonic acids are described. Physico-chemical properties of synthesized derivatives are
CHARACTERIZATION OF 1-AMINOALKANEPHOSPHONIC ACIDS BY CHEMICAL IONIZATION MASS SPECTROMETRY
Kudzin, Zbigniew H.,Drabowicz, Jozef,Sochacki, Marek,Wisniewski, Witold
, p. 77 - 94 (2007/10/02)
Chemical ionization mass spectra (CIMS and DCIMS) of 1-aminoalkanephosphonic acids 1 and their diester derivatives 3 are reported and they are discussed in the context of structural determination. Key words: 1-aminoalkanephosphonic acods, chemical ionizat
An Amidoalkylation of Trivalent Phosphorus Compounds with P(O)H Functions Including Acetic Acid Solutions of PCl3, RPCl2 or R2PCl, Diesters of Phosphorous Acid and Phosphorus-III-Acids
Oleksyszyn, Jozef
, p. 19 - 28 (2007/10/02)
An amidoalkylation of PCl3 or its organic derivatives in acetic acid solution takes place because equilibrium between AcOH and >P-Cl exist, leading to hydroxychlorophosphines.Those last compounds undergo an amidoalkylation like other nucleophiles.Based on these data, it was shown that an amidoalkylation reaction is usual for all phosphorus compounds with the R2P(O)H system and provides derivatives with the >N-C-P(O)R2 functions.The scope and limitation of these reactions are discussed.
