82721-80-0Relevant articles and documents
Radical-mediated sulfonyl alkynylation, allylation, and cyanation of propellane
Wu, Zhen,Xu, Yaohui,Zhang, Huihui,Wu, Xinxin,Zhu, Chen
supporting information, p. 6066 - 6069 (2021/06/21)
Bicyclo[1.1.1]pentane (BCP) is widely applied as the bioisostere for aryl, internal alkynes, andtert-butyl groups in medicinal chemistry. We herein disclose an efficient and practical preparation of sulfonyl alkynyl/allyl/cyano-substituted BCP derivatives
Boryl Radical-Mediated C?H Activation of Inactivated Alkanes for the Synthesis of Internal Alkynes
Han, Jia-Bin,San, Htet Htet,Guo, Ao,Wang, Long,Tang, Xiang-Ying
supporting information, p. 2366 - 2370 (2020/11/30)
An intriguing pyridine-boryl radical-mediated C?H alkynylation reaction of inactivated alkanes was described. The reaction features mild operation condition and wide substrate scope, and affords the corresponding products in moderate to good yields. Notab
Copper-Catalyzed Intermolecular Alkynylation and Allylation of Unactivated C(sp3)-H Bonds via Hydrogen Atom Transfer
Liang, Lei,Guo, Ge,Li, Chen,Wang, Song-Lin,Wang, Yue-Hui,Guo, Hai-Ming,Niu, Hong-Ying
supporting information, p. 8575 - 8579 (2021/11/13)
We describe Cu-catalyzed intermolecular alkynylation and allylation of unactivated C(sp3)-H bonds with singly occupied molecular orbital-philes (SOMO-philes) via hydrogen atom transfer (HAT). Employing N-fluoro-sulfonamide as a HAT reagent, a set of subst
Electrochemical decarboxylative sulfonylation of arylacetylenic acids with sodium arylsulfinates: Access to arylacetylenic sulfones
Zhong, Qihao,Zhao, Yongli,Sheng, Shouri,Chen, Junmin
supporting information, p. 161 - 167 (2019/12/03)
An efficient decarboxylative sulfonylation of arylacetylenic acids with sodium arylsulfinates has been achieved by an electro-oxidative strategy. This novel protocol offers a simple, efficient, and green route to a series of arylacetylenic sulfones in mod
Mukaiyama reagent-promoted metal-free preparation of alkynyl sulfones and phosphonates under mild conditions
Qi, Danyang,Dong, Wanrong,Peng, Zhihong,Zhang, Yingjun,An
, (2019/08/01)
An efficient and mild route for the formation sulfur or phosphor-substituted alkynes was herein demonstrated. The Mukaiyama reagent-mediated transformation started from easily-accessible substrates without carbon-carbon triple bonds, and the reaction proceeded under mild conditions (room temperature) in a one-pot manner, requiring for no transition metal-catalysts. The practical protocol featured for good functional groups tolerance (up to 41 examples) and high efficiency (up to 91% yields) towards alkynyl sulfones and alkynyl phosphonates at low cost.
Synthesizing method of acetyleic sulfone
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Paragraph 0037-0057, (2019/03/28)
The invention provides a synthesizing method of acetyleic sulfone. The synthesizing method comprises the following steps of mixing a primer which is shown in the description, 2-chloro-1-methylpyridinium iodide, an alkaline substance and an organic solvent
Regiodivergent Rhodium(I)-Catalyzed Azide-Alkyne Cycloaddition (RhAAC) to Access Either Fully Substituted Sulfonyl-1,2,3-triazoles under Mild Conditions
Song, Wangze,Zheng, Nan,Li, Ming,Dong, Kun,Li, Junhao,Ullah, Karim,Zheng, Yubin
supporting information, p. 6705 - 6709 (2018/11/02)
A regiodivergent Rh(I)-catalyzed azide-alkyne cycloaddition (RhAAC) was developed for the synthesis of both fully substituted 4-sulfonyl-1,2,3-triazoles and 5-sulfonyl-1,2,3-triazoles in high regioselectivities and yields under mild conditions in one step
Br?nsted Base Assisted Photoredox Catalysis: Proton Coupled Electron Transfer for Remote C?C Bond Formation via Amidyl Radicals
Jia, Jiaqi,Ho, Yee Ann,Bülow, Raoul F.,Rueping, Magnus
, p. 14054 - 14058 (2018/09/14)
The synthesis of alkyne- and alkene-decorated lactams has been achieved through a photoredox-initiated radical cascade reaction. The developed Br?nsted base assisted, photoredox-catalyzed, intramolecular 5-exo-trig cyclization/intermolecular radical addit
Direct cross-coupling of aryl alkynyliodines with arylsulfinic acids leading to alkynyl sulfones under catalyst-free conditions
Wang, Leilei,Wei, Wei,Yang, Daoshan,Cui, Huanhuan,Yue, Huilan,Wang, Hua
supporting information, p. 4799 - 4802 (2017/11/27)
A facile and efficient one-pot method has been developed for the construction of alkynyl sulfones via direct cross-coupling reaction of aryl alkynyliodines and arylsulfinic acids. The present transformation could be accomplished under catalyst- and additive-free conditions, providing a series of alkynyl sulfones in moderate to good yields with favorable functional group tolerance.
Consecutive visible-light photoredox decarboxylative couplings of adipic acid active esters with alkynyl sulfones leading to cyclic compounds
Li, Jingjing,Tian, Hua,Jiang, Min,Yang, Haijun,Zhao, Yufen,Fu, Hua
, p. 8862 - 8864 (2016/07/22)
Novel and efficient consecutive photoredox decarboxylative couplings of adipic acid active esters (bis(1,3-dioxoisoindolin-2-yl)-substituted hexanedioates) with substituted 1-(2-arylethynylsulfonyl)benzenes have been developed under visible-light photocatalysis. The successive photoredox decarboxylative C-C bond formation at room temperature afforded the corresponding cyclic compounds in good yields with tolerance of some functional groups.
