828-80-8

Upstream product

• 617721-48-9 (1-methyl-5-phenyl-pyrrol-2-yl)-acetic acid 
• 1008-89-5 2-phenylpyridine 
• 137387-48-5 1-methyl-5-phenyl-1H- pyrrole-2-carboxaldehyde 
• 52806-02-7 iodure de 1-methyl-2-phenylpyridinium 
• 74-89-5 methylamine 
• 583-05-1 1-phenylpentane-1,4-dione 
• 98960-25-9 1-Methyl-5-oxo-Δ²-pyrrolinyl-essigsaeure-(2)-ethylester 
• 600-29-3 1,2-dimethylpyrrole 
• 98-09-9 benzenesulfonyl chloride 
• 733747-67-6 (1-methyl-5-phenyl-pyrrol-2-yl)-acetic acid ethyl ester 

Downstream Products

• 15364-06-4 1,5-dimethyl-2,4-diphenylpyrrole 
• 1260147-09-8 C₁₈H₁₆IN 
• 1260147-08-7 C₁₈H₁₆BrN 

Relevant academic research and scientific papers

Synthesis of 2-Formylpyrroles from Pyridinium Iodide Salts

The first I2-mediated synthesis of 2-formylpyrroles from pyridinium salts is reported. This protocol enables the synthesis of diversely substituted 2-formylpyrroles in good yields under operationally simple conditions. The detailed mechanistic studies reveal that the reaction proceeds via a novel H2O-triggered ring opening of the pyridinium salt and a subsequent intramolecularly nucleophilic addition sequence.

Visible-light photocatalyzed synthesis of 2-aryl N-methylpyrroles, furans and thiophenes utilizing arylsulfonyl chlorides as a coupling partner

Visible-light (Blue LED lamp: hν=425±15 nm) photocatalyzed cross-coupling reactions of arylsulfonyl chloride with N-methylpyrrole, furan, thiophene and their derivatives have been achieved in moderate to good yields at room temperature. A plausible mechan

Palladium-catalyzed C-H arylation of 2,5-substituted pyrroles

The palladium-catalyzed direct arylation of 2,5-substituted pyrrole derivatives with diaryliodonium salts to generate tri-, tetra-, and penta-substituted pyrrole products is described. The scope and limitations of these transformations are also reported.