82801-81-8

Basic information

• Product Name: 3,4-Methylenedioxy-N-ethylamphetamine
• Synonyms: 3,4-methylenedioxyethamphetamine;(+/-)-3,4-METHYLENEDIOXYETHYLAMPHETAMINE;AURORA KA-7747;1,3-Benzodioxole-5-ethanamine, N-ethyl-alpha-methyl-, hydrochloride;3,4-METHYLENDIOXYETHYLAMPHETAMIN;3,4-METHYLENEDIOXY-N-ETHYLAMPHETAMINE;3,4-METHYLENDIOXYETHYLAMPHETAMIN, >99% (HPLC);N-Ethyl-1-(3,4-methylenedioxyphenyl)-2-propylamine
• CAS NO: 82801-81-8
• Molecular Formula: C₁₂H₁₇NO₂
• Molecular Weight: 207.27
• EINECS: 200-659-6
• Mol File: 82801-81-8.mol
• Article Data: 2

Chemical Properties

• Melting Point: 140-145 °C
• Boiling Point: bp0.2 85-95°
• Flash Point: 9℃
• Appearance: white crystalline powder
• Density: 1.078 g/cm³
• Vapor Pressure: 0.00117mmHg at 25°C
• Refractive Index: 1.53
• Storage Temp.: 2-8°C
• PKA: 10.34±0.19(Predicted)
• CAS DataBase Reference: 3,4-Methylenedioxy-N-ethylamphetamine(CAS DataBase Reference)
• NIST Chemistry Reference: 3,4-Methylenedioxy-N-ethylamphetamine(82801-81-8)
• EPA Substance Registry System: 3,4-Methylenedioxy-N-ethylamphetamine(82801-81-8)

Safety Data

• Hazard Codes: Xi,T,F
• Statements: 36/37/38-39/23/24/25-23/24/25-11
• Safety Statements: 26-36-45-36/37-16-7
• RIDADR: UN1230 - class 3 - PG 2 - Methanol, solution
• WGK Germany: 1
• Hazardous Substances Data: 82801-81-8(Hazardous Substances Data)

Usage

Uses

Methylenedioxyethamphetamine is a illegal psychoactive substance.

Hazard

Human systemic effects.

InChI:InChI=1/C12H17NO2/c1-3-13-9(2)6-10-4-5-11-12(7-10)15-8-14-11/h4-5,7,9,13H,3,6,8H2,1-2H3

Upstream product

• 4676-39-5 1-(1,3-benzodioxol-5-yl)-2-propanone 
• 557-66-4 ethanamine hydrochloride 
• 75-04-7 ethylamine 
• 5438-41-5 5-(2-nitroprop-1-enyl)benzo[d][1,3]dioxole 
• 4764-17-4 3,4-methylenedioxyamphetamine 
• 36209-71-9 N-[1-methyl-2-(3,4-methylenedioxyphenyl)ethyl]acetamide 

Downstream Products

• 4764-17-4 3,4-methylenedioxyamphetamine 

Relevant articles and documents

Research on the central activity and analgesia of N-substituted analogs of the amphetamine derivative 3,4-methylenedioxyphenylisopropylamine

N-substituted analogs of 3,4-methylenedioxyphenylisopropylamine (MDA) were tested ror analgesic potency and influence on motor activity in mice following potency and influence on motor activity in mice following oral administration. These compounds also were tested for thei psychotomimetic potency in man. Unsubstituted MDA and its monoalkyl-homologs with a low number of C-atoms (N-methyl-, N-methyl-, N-ethyl-MDA) showed both enhancement of motor-activity in mice and psychotomimetic effects in man. MDA and N-methyl-MDA also showed an analgesic effec wthich was enhanced by the inclusion of a weakly labis group (N-mallyl, N-hydroxyethyl). These latter two compounds, however, did not influence motor-activity, which makes them more recommendable as possible analgesic compounds. Structural parallels between these compounds, morphine, endorphins and enkephalins, may explain their similar spectrum of pharmacological effects.