82807-38-3

Upstream product

• 5180-78-9 methyl 2-(2-methoxyphenyl)-2-oxoacetate 
• 612-15-7 o-methoxystyrene 
• 67-56-1 methanol 
• 135-02-4 ortho-anisaldehyde 
• 6814-64-8 methylenedimethyl sulfurane 

Downstream Products

• 340963-76-0 thiocarbonic acid O-[7-acetylamino-1-(tert-butyl-diphenyl-silanyloxymethyl)-8-methoxy-2-(4-methoxy-benzyl)-3-oxo-1,2,3,4-tetrahydro-isoquinolin-4-yl] ester O-phenyl ester 
• 340963-78-2 thiocarbonic acid O-[7-acetylamino-2-allyl-1-(tert-butyl-diphenyl-silanyloxymethyl)-8-methoxy-3-oxo-1,2,3,4-tetrahydro-isoquinolin-4-yl] ester O-phenyl ester 
• 340963-48-6 (R)-acetic acid [[1-(3-acetylamino-2-methoxyphenyl)-2-(tert-butyldiphenylsilanyloxy)ethyl]-(4-methoxybenzyl)carbamoyl]methyl ester 
• 340963-55-5 (R)-N-[1-(tert-butyldiphenylsilanyloxy)-4-hydroxy-8-methoxy-2-(4-methoxybenzyl)-3-oxo-1,2,3,4-tetrahydroisoquinolin-7-yl]acetamide 
• 340963-46-4 (R)-acetic acid [[2-(tert-butyldiphenylsilanyloxy)-1-(2-methoxy-3-nitrophenyl)ethyl]-(4-methoxybenzyl)carbamoyl]methyl ester 
• 340963-51-1 (R)-N-[1-(3-acetylamino-2-methoxyphenyl)-2-(tert-butyldiphenylsilanyloxy)ethyl]-2-hydroxy-N-(4-methoxybenzyl)acetamide 
• 340963-53-3 N-[1-(3-acetylamino-2-methoxy-phenyl)-2-(tert-butyl-diphenyl-silanyloxy)-ethyl]-N-(4-methoxy-benzyl)-2-oxo-acetamide 
• 340963-64-6 (R)-acetic acid {[1-(3-acetylamino-2-methoxyphenyl)-2-(tert-butyldiphenylsilanyloxy)ethyl]allylcarbamoyl}methyl ester 
• 340963-67-9 N-[(1R,4S)-2-allyl-1-(tert-butyldiphenylsilanyloxymethyl)-4-hydroxy-8-methoxy-3-oxo-1,2,3,4-tetrahydroisoquinolin-7-yl]acetamide 
• 340963-68-0 (R)-N-[2-allyl-1-(tert-butyldiphenylsilanyloxymethyl)-8-methoxy-3-oxo-1,2,3,4-tetrahydroisoquinolin-7-yl]acetamide 
• 340963-66-8 (R)-N-[1-(3-acetylamino-2-methoxyphenyl)-2-(tert-butyldiphenylsilanyloxy)ethyl]-N-allyl-2-hydroxyacetamide 
• 340963-62-4 (R)-acetic acid {allyl-[2-(tert-butyldiphenylsilanyloxy)-1-(2-methoxy-3-nitrophenyl)ethyl]carbamoyl}methyl ester 
• 340963-75-9 (S)-2-[2-(tert-butyldiphenylsilanyloxy)-1-(2-methoxy-3-nitrophenyl)ethyl]isoindole-1,3-dione 
• 340963-70-4 (R)-N-[1-(tert-butyldiphenylsilanyloxymethyl)-8-methoxy-3-oxo-2-propenyl-1,2,3,4-tetrahydroisoquinolin-7-yl]acetamide 

Relevant academic research and scientific papers

Ru-MACHO-Catalyzed Highly Chemoselective Hydrogenation of α-Keto Esters to 1,2-Diols or α-Hydroxy Esters

A ruthenium pincer catalyst has been shown to be highly effective for the hydrogenation of a wide range of α-keto esters, affording either diols or hydroxy esters depending on the choice of reaction conditions. Strong base, high temperature, and pressure favor the formation of diols whilst the opposite is true for the hydroxy esters.

Bacterial monooxygenase mediated preparation of nonracemic chiral oxiranes: Study of the effects of substituent nature and position

Monooxygenation of styrene derivatives using recombinant E. coli biocatalyst is an efficient way to prepare the corresponding oxiranes. The electronic and geometric effects of the ring substituents are described and show the relaxed specificity of the enzyme and its high stereoselectivity.

New uses for the Burgess reagent in chemical synthesis: Methods for the facile and stereoselective formation of sulfamidates, glycosylamines, and sulfamides

Although the Burgess reagent (methoxycarbonylsulfamoyltriethylammonium hydroxide, inner salt) has found significant use in chemical synthesis as a dehydrating agent, almost no work has been directed towards its potential in other synthetic applications. As this article will detail, we have found that the Burgess reagent is remarkably effective at accomplishing a number of non-dehydrative synthetic tasks when applied to appropriate substrates, such as the formation of sulfamidates from 1,2-diols or epoxyalcohols, α- and β-glycosylamines from carbohydrates, and cyclic sulfamides from 1,2-aminoalcohols. Beyond delineating the power of these new reaction manifolds, we also describe the construction of a group of alternative Burgess-type reagents that extends the scope of these new reactions even further.

Novel self-coupling reaction of cyclic ketones under a high-pressure mercury lamp

A novel self-coupling reaction in alcohol or hexane-water of cycloalkanone (cycloheptanone, cyclooctanone, and cyclododecanone) with irradiation under a high-pressure mercury lamp yielded the corresponding pinacol-type compound in good yields. In the case of cyclohexanone, 2-methyl-, 2-phenyl-, 4-methylcyclohexanone, 5α- and 5β-cholestan-3-one, the pinacol derivatives were not obtained and the dimethyl acetals were given.