869475-52-5

Upstream product

• 159768-51-1 2-amino-4-fluoro-5-methoxybenzoic acid methyl ester 
• 463-52-5 formamidine 
• 82846-18-2 4?fluoro-3-methoxybenzoic acid 
• 159768-50-0 methyl 4-fluoro-5-methoxy-2-nitrobenzoate 
• 77287-34-4 formamide 
• 74385-37-8 methyl 4-fluoro-3-methoxy-benzoate 

Downstream Products

• 264208-72-2 4-chloro-6-methoxy-7-[(1'-methylpiperidin-4'-yl)methoxy]-quinazoline 
• 1356000-47-9 C₂₉H₃₀F₂N₆O₃ 
• 1356000-45-7 C₂₉H₃₁FN₆O₃ 
• 264208-69-7 6-methoxy-7-[(1-methylpiperidin-4-yl)methoxy]-3,4-dihydroxyquinazolin-4-one 
• 162012-60-4 4-(3-chloro-4-fluoroanilino)-6-methoxy-7-fluoroquinazoline 
• 159768-48-6 4-chloro-7-fluoro-6-methoxyquinazoline 

Relevant academic research and scientific papers

BICYCLIC ETHER O-GLYCOPROTEIN-2-ACETAMIDO-2-DEOXY-3-D-GLUCOPYRANOSIDASE INHIBITORS

Described herein are compounds represented by formula (I) or a pharmaceutically acceptable salt thereof, pharmaceutical compositions comprising the same and methods of preparing and using the same. The variables Ar, X, R1, R3, R 4, Y1, Y2, n and p are as defined herein.

Facile synthesis of 7-amino anilinoquinazolines via direct amination of the quinazoline core

The facile preparation of 4-(3-chloro-4-fluoroanilino)-6-alkoxy-7- aminoquinazolines from their corresponding 7-triflate and 7-fluoro precursors are highlighted.