82891-84-7

Upstream product

• 52710-27-7 4-propylbenzoyl chloride 
• 2576-47-8 2-bromoethylamine hydrobromide 
• 122-01-0 4-chloro-benzoyl chloride 
• 51847-02-0 4-chloro-N-(2-chloroethyl)benzamide 
• 7400-54-6 4-chloro-N-(2-hydroxyethyl)-benzamide 
• 927-77-5 n-propylmagnesium bromide 
• 7399-68-0 2-(4-chlorophenyl)-4,5-dihydro-1,3-oxazole 

Relevant academic research and scientific papers

Potentiation of the fosmidomycin analogue FR 900098 with substituted 2-oxazolines against Francisella novicida

A library of 33 compounds was screened for potentiation of the antibiotic FR 900098 against the Francisella tularensis surrogate Francisella novicida. From the screen a highly potent 2-oxazoline adjuvant was discovered capable of potentiating FR 900098 with a 1000-fold reduction in MIC against the Francisella sub-species F. novicida and F. philomiragia.

Oxazolines. 3. Regioselective Synthesis of 2-(Monosubstituted phenyl) and/or Unsymmetrically 2-(Disubstituted phenyl) 2-Oxazolines by Cross-Coupling Grignard Reagents to (Haloaryl)-2-oxazolines

2-(Monosubstituted phenyl) 2-oxazoline 5 (R = H) and unsymmetrically 2-(disubstituted phenyl) 2-oxazolines 5 have been prepared by cross-coupling alkyl and aryl Grignard reagents to 2-(mono- and dihalogenated phenyl) 2-oxazolines 2 and 3 (X = halogen), re