82911-72-6

Usage

Molecular composition

One molecule of 2,5-pyrrolidinedione, 1-hydroxyand one molecule of N-cyclohexylcyclohexanamine.

Structure

A cyclic organic compound with a hydroxy group (2,5-pyrrolidinedione, 1-hydroxy-) and a primary amine compound (N-cyclohexylcyclohexanamine).

Uses

May be used in various industrial and research applications, depending on the specific properties and context in which it is being utilized.

Upstream product

• 74124-79-1 di(succinimido) carbonate 
• 6066-82-6 1-hydroxy-pyrrolidine-2,5-dione 
• 101-83-7 N-cyclohexyl-cyclohexanamine 

Downstream Products

• 66065-85-8 succinimidyl 2,2,2-trichloroethyl carbonate 
• 556050-48-7 carbonic acid 2,5-dioxopyrrolidin-1-yl ester 4-(3,3,4,4,5,5,6,6,7,7,8,8,8-tridecafluorooctyl)benzyl ester 
• 556050-49-8 carbonic acid 2,5-dioxopyrrolidin-1-yl ester 4-(3,3,4,4,5,5,6,6,7,7,8,8,9,9,10,10,10-heptadecafluorodecyl)benzyl ester 
• 82911-76-0 N-(9-fluorenylmethyloxycarbonyl)-L-threonine*DCHA 
• 82911-77-1 2-(9H-fluoren-9-ylmethoxycarbonylamino)-3-(4-hydroxyphenyl)propionic acid benzyl ester 
• 82911-79-3 N-(fluorenyl-9-methoxycarbonyl)-L-tyrosine methyl ester 
• 73731-37-0 Fmoc-Thr-OH 
• 68858-20-8 Fmoc-Val-OH 
• 1145-80-8 N-(benzyloxycarbonyl)-L-serine 
• 252668-50-1 N-[(E)-2-(methylsulfonyl)-3-phenyl-2-propenyloxycarbonyloxy]succinimide 
• 197244-91-0 N-(benzothiophenesulfone-2-methyl)-N-succinimidyl carbonate 
• 13139-17-8 N-(Benzyloxycarbonyloxy)succinimide 
• 82911-69-1 N-(9H-fluoren-2-ylmethoxycarbonyloxy)succinimide 
• 15149-73-2 2,5-dioxopyrrolidin-1-yl carbonochloridate 

Relevant academic research and scientific papers

METHOD FOR PREPARING ACTIVATED ESTERS

The invention relates to a method for preparing an activated ester of the formula (I), where R is a (C1-C6) alkyl, aryl, heteroaryl, cycloalkyl, or heterocycloalkyl group, and ALK is a (C1-C6) alkylene group, said method consisting of reacting the dicyclohexylamine P1 salt and the disuccinimidyl carbonate (DSC) in a solvent in which the dicyclohexylamine salt of the N-hydroxysuccinimide P2 is precipitated. The invention also relates to products of the formula P1.

Introduction of 9-fluorenylmethyloxycarbonyl, trichloroethoxycarbonyl, and benzyloxycarbonyl amine protecting groups into O-unprotected hydroxyamino acids using succinimidyl carbonates

9-Fluorenylmethyl succinimidyl, pentachlorophenyl, and benzotriazole-1-yl carbonates were prepared and their reactivity with L-serine and L-serine benzyl ester was compared.The most efficient reagent, 9-fluorenylmethyl succinimidyl carbonate, was used for the preparation of 9-flourenylmethyloxycarbonyl derivatives of other hydroxyamino acids and hydroxyamino acid esters in high yields.The use of trichloroethyl and benzyl succinimidyl carbonates for an efficient conversion of hydroxyamino acids and their esters into the corresponding N-trichloroethoxycarbonyl and benzyloxycarbonyl derivatives is described.