82956-51-2

Upstream product

• 15231-91-1 6-bromo-naphthalen-2-ol 
• 60-29-7 diethyl ether 
• 82957-06-0 6-amidino-2-naphthol methanesulfonate 
• 52927-22-7 6-cyano-2-naphthol 
• 75-75-2 methanesulfonic acid 
• 82956-71-6 (E)-3-Phenyl-acrylic acid 6-carbamimidoyl-naphthalen-2-yl ester; compound with methanesulfonic acid 
• 58200-88-7 6-Amidino-2-naphthol 
• 765871-54-3 6-Hydroxy-naphthalene-2-carboximidic acid methyl ester 

Relevant academic research and scientific papers

AMIDINE COMPOUND

Amidino compounds represented by the formula STR1 and pharmaceutically acceptable acid addition salts thereof are novel compounds and are useful as powerful antitrypsine, antiplasmin, antikallikrein and antithrombin agents. Having strong anti-C1 (C1r, C1s) activities and an anticomplement activity, they are also useful as anticomplement agents. These amidino compounds are prepared by usual esterification of carboxylic acid compounds represented by the formula STR2 with 6-amidino-2-naphthol and, if necessary, can be transformed into pharmaceuticlly acceptable acid addition salts thereof.