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Usage

Uses

Used in Pharmaceutical Industry:
3-Fluoro-5-iodoaniline is used as an intermediate in the synthesis of various pharmaceuticals. Its unique structure allows it to be a key component in the development of new drugs, particularly those targeting specific biological pathways or receptors.
Used in Agrochemical Industry:
In the agrochemical sector, 3-Fluoro-5-iodoaniline serves as an intermediate for the production of pesticides and other agricultural chemicals. Its properties make it suitable for creating compounds that can effectively control pests and diseases in crops.
Used in Dye Industry:
3-Fluoro-5-iodoaniline is utilized in the dye industry for the creation of new dye molecules. Its presence in the molecular structure can influence the color and stability of the dyes, making it a valuable component in the development of novel dyes for various applications.
Used in Organic Chemistry:
3-Fluoro-5-iodoaniline is also used as a building block in organic chemistry for the creation of more complex molecules. Its reactivity and the presence of both fluorine and iodine atoms make it a versatile compound for use in organic synthesis and the development of new chemical entities.

Upstream product

• 861547-81-1 1,2-dichloro-3-iodo-5-nitro-benzene 
• 123158-76-9 1-chloro-3-iodo-5-nitrobenzene 
• 123158-75-8 2-amino-5-chloro-3-nitrophenyliodide 
• 89-63-4 4-Chloro-2-nitroaniline 
• 146512-91-6 5-nitro-4-chloro-2-iodoaniline 
• 7439-89-6 iron 
• 121-87-9 2-Chloro-4-nitroaniline 
• 861609-74-7 2-chloro-6-iodo-4-nitroaniline 
• 99-54-7 3,4-dichloronitrobenzene 

Downstream Products

• 139422-22-3 N-(3-chloro-5-iodophenyl)(hydroxyimino)acetamide 
• 139422-28-9 4-Chloro-2-(2-ethoxycarbonyl-acetylamino)-6-iodo-benzoic acid methyl ester 
• 139422-27-8 methyl 2-amino-4-chloro-6-iodobenzoate 
• 139422-25-6 2-amino-4-chloro-6-iodobenzoic acid 

Relevant academic research and scientific papers

Pd-Catalyzed Decarboxylative Ortho-Halogenation of Aryl Carboxylic Acids with Sodium Halide NaX Using Carboxyl as a Traceless Directing Group

A highly regioselective Pd-catalyzed carboxyl directed decarboxylative ortho-C-H halogenation of cheap o-nitrobenzoic acids with NaX (X = I, Br) under aerobic conditions has been established. The utility of the method has been demonstrated by the gram-scale reaction and derivatization of the product. Experimental results have confirmed Pd and Bi played critical roles in the transformation and indicated the transformation might proceed via 2-halo-6-nitrobenzoic acid derivative intermediate.

Kynurenic acid derivatives useful in the treatment of neurodegenerative disorders

4-Oxo-1,4-dihydroquinoline compounds having a 2-acidic group or a group convertible thereto in vivo, and their pharmaceutically acceptable salts, are potent specific antagonists of N-methyl-D-aspartate (NMDA) receptors and are therefore useful in the treatment of neurodegenerative disorders. 4-Oxo-1,4-dihydroquinoline compounds having a 2-acidic group or a group convertible thereto in vivo, other than carboxy or C 1-6 alkoxycarbonyl, are novel compounds, as also are compounds of formula II STR1 wherein R 2 represents carboxy or a group convertible thereto in vivo, R 6 is hydrogen and R 5 and R 7 represent C 1-6 alkyl or halogen, provided that R 5 and R 7 are not simultaneously chlorine or simultaneously bromine; a process for preparing the novel compounds is described, as also are pharmaceutical compositions containing the novel compounds.

Kynurenic Acid Derivatives. Structure-Activity Relationships for Excitatory Amino Acid Antagonism and Identification of Potent and Selective Antagonists at the Glycine Site of the N-Methyl-D-aspartate Receptor

Derivatives of the nonselective excitatory amino acid antagonist kynurenic acid (4-oxo-1,4-dihydroquinoline-2-carboxylic acid, 1) have been synthesized and evaluated for in vitro antagonist activity at the excitatory amino acid receptors sensitive to N-me