83188-31-2

Upstream product

• 1483-82-5 phenylethynyl chloride 
• 97-62-1 Ethyl isobutyrate 
• 600-00-0 ethyl 2-bromoisobutyrate 
• 536-74-3 phenylacetylene 

Downstream Products

• 15116-34-4 2,2-dimethyl-4-oxo-4-phenylbutanoic acid 
• 1015792-27-4 3,3-dimethyl-5-phenyl-4-phenylseleno-2(3H)-furanone 
• 1015792-25-2 4-iodo-3,3-dimethyl-5-phenyl-2(3H)-furanone 
• 1015792-26-3 4-chloro-3,3-dimethyl-5-phenyl-2(3H)-furanone 
• 940965-20-8 2, 2-dimethyl-4-phenylbut-3-yn-1-ol 
• 1580548-39-5 C₁₂H₁₃⁽²⁾HO 
• 79238-23-6 (3E)-2,2-dimethyl-4-phenyl-3-butenal 
• 15732-83-9 (E)-2,2-dimethyl-4-phenyl-3-buten-1-ol 
• 949028-84-6 4,4-dimethyl-6-phenylhexa-1,5-diyn-3-yl acetate 
• 949028-83-5 4,4-dimethyl-6-phenylhexa-1,5-diyn-3-ol 
• 949028-47-1 4,4-dimethyl-1,6-diphenylhexa-1,2-dien-5-yne 
• 949028-82-4 2,2-dimethyl-4-phenylbut-3-ynal 

Relevant academic research and scientific papers

Transition-Metal-Free Coupling of Alkynes with α-Bromo Carbonyl Compounds: An Efficient Approach towards β,γ-Alkynoates and Allenoates

A direct transition-metal-free coupling between alkynes and α-bromo carbonyl compounds has been developed with ultraviolet (UV) light in aqueous media. This method represents a facile approach to synthetically useful β,γ-alkynyl esters and amides stereoselectively from two readily available starting materials. As an example of the synthetic application of the products, the alkynyl esters were readily converted into allenoates. Time for UV! A direct coupling between alkynes and α-bromo compounds has been developed with ultraviolet light in aqueous media (see scheme). This method represents a facile approach to synthetically useful β,γ-alkynyl esters and amides stereoselectively from two readily available starting materials.

The mechanism of gold(I)-catalyzed hydroalkoxylation of alkynes: An extensive experimental study

An extensive experimental study of the mechanism of gold(I)-catalyzed hydroalkoxylation of internal alkynes has been conducted by using NMR spectroscopy. This study was focused on the organogold intermediates, observations of actual catalytic intermediates in situ, and the reaction kinetics that are involved in this reaction. Based on the experimental results, a complete mechanistic picture was established, including on- and off-cycle processes that explain the role of diaurated species. We have shown that gold-catalyzed hydroalkoxylation of internal alkynes is a reaction that requires only one gold atom for the catalytic cycle, disproving a recent hypothesis regarding the involvement of cooperative gold catalysis.

Gold-catalyzed synthesis of bicyclo[4.3.0]nonadiene derivatives via tandem 6-endo-dig/Nazarov cyclization of 1,6-allenynes

(Chemical Equation Presented) Catalytic cyclization of 1,6-allenynes was achieved by AuPPh3SbF6 (5 mol %) in cold CH 2Cl2 (0°C, 0.5-4 h) to form bicyclo[4.3.0]nonadiene products; this cyclization proceeded more

CHLOROACETYLENES AS MICHAEL ACCEPTORS. II. DIRECT ETHYNYLATION AND VINYLATION OF TERTIARY ENOLATES.

The reaction of ClCCCl, PhCCCl and PhSCCCl with a variety of tertiary enolates leads in 43-90percent yields to α-chloroethynyl, α-phenylethynyl and α-thiophenylethynyl derivatives.The -CCCl group is smoothly converted to -CCH using copper p