92339-07-6

Basic information

• Product Name: 2,3,5,6-Tetrafluoro-1,4-benzenedimethanol
• Synonyms: 2,3,5,6-Tetrafluoro-1,4-benzenedimethanol;2,3,5,6-TETRAFLUORO-4-HYDROXYMETHYLPHENYLMETHANOL;Tetrafluoro-4-(hydroxymethyl)phenyl]methanol;2,3,5,6-Tetrafluoroterephthalyl alcohol;(2,3,5,6-Tetrafluoro-phenyl)dimethanol;2,3,5,6-tetrafluoro tetre xylene-diol;1,2,4,5-TETRAFLUORO-3,6-DIHYDROXYMETHYL BENZENE;2,3,5,6-tetrafluoro-1,4-Benzene dimethanlo
• CAS NO: 92339-07-6
• Molecular Formula: C₈H₆F₄O₂
• Molecular Weight: 210.13
• EINECS: 1533716-785-6
• Product Categories: Aromatic Halides (substituted)
• Mol File: 92339-07-6.mol
• Article Data: 23

Chemical Properties

• Melting Point: 127.0 to 131.0 °C
• Boiling Point: 255.979 °C at 760 mmHg
• Flash Point: 108.613 °C
• Appearance: Light yellow crystal
• Density: 1.569 g/cm³
• Vapor Pressure: 0.00815mmHg at 25°C
• Refractive Index: 1.496
• Storage Temp.: Sealed in dry,Room Temperature
• PKA: 12.55±0.10(Predicted)
• CAS DataBase Reference: 2,3,5,6-Tetrafluoro-1,4-benzenedimethanol(CAS DataBase Reference)
• NIST Chemistry Reference: 2,3,5,6-Tetrafluoro-1,4-benzenedimethanol(92339-07-6)
• EPA Substance Registry System: 2,3,5,6-Tetrafluoro-1,4-benzenedimethanol(92339-07-6)

Safety Data

• Hazardous Substances Data: 92339-07-6(Hazardous Substances Data)

Usage

InChI:InChI=1/C8H6F4O2/c9-5-3(1-13)6(10)8(12)4(2-14)7(5)11/h13-14H,1-2H2

Upstream product

• 3217-47-8 2,3,5,6-tetrafluoroterephthalaldehyde 
• 652-36-8 2,3,5,6-tetrafluoroterephthalic acid 
• 123-91-1 1,4-dioxane 
• 7440-02-0 nickel 
• 95-50-1 1,2-dichloro-benzene 
• 1634-04-4 tert-butyl methyl ether 
• 727-55-9 dimethyl 2,3,5,6-tetrafluoroterephthalate 
• 106-42-3 para-xylene 
• 64-19-7 acetic acid 
• 802294-64-0 propionic acid 
• 131803-37-7 α,α'-dichloro-2,3,5,6-tetrafluoro-1,4-xylene 
• 1242014-43-2 N,N,N',N'-tetrakis(tert-butoxycarbonyl)-(2,3,5,6-tetrafluoro benzene)-1,4-biscarboxamide 

Downstream Products

• 83282-91-1 2,3,5,6-tetrafluoro-4-(methoxymethyl)benzyl alcohol 
• 79538-03-7 2,3,5,6-tetrafluoro-4-methylbenzyl alcohol 
• 703-87-7 1,4-dimethyl-2,3,5,6-tetrafluorobenzene 
• 99705-45-0 4-chloromethyl-2,3,5,6-tetrafluorobenzyl alcohol 
• 776-40-9 α,α’-dibromo-m-tetrafluoroxylene 
• 99705-46-1 4-(hydroxymethyl)-2,3,5,6-tetrafluorobenzyl bromide 
• 3217-47-8 2,3,5,6-tetrafluoroterephthalaldehyde 
• 131803-39-9 2,3,5,6-tetrafluoro-1,4-xylene-α,α'bis(diethylsulphonium chloride) 
• 288627-04-3 [4-((diethoxyphosphoryl)methyl)-2,3,5,6-tetrafluorobenzyl]phosphonic acid diethyl ester 

Relevant articles and documents

A substituted aromatic alcohols of the economical efficiency of the synthesis process (by machine translation)

The invention discloses a substituted aromatic alcohols of the economical efficiency of the synthesis process, the COOR1 - C6 F4 - COOR1 (R1 Representative C1 - C4 Alkyl) to the organic solvent in the input, in the NaBH4 Under the action of the shall CH reduction reaction2 OH - C6 F4 - CH2 OH (II) and CH2 OH - C6 F4 - COOH (III); the mixture is dissolved in a weak acid buffer solution, after adjusting the pH of the extraction, the aqueous layer containing in II, III contained in the oil reservoir; the oil reservoir into the non-protic solvent removes the carboxyl, shall be CH2 OH - C6 HF4 . The present invention, reduction process residence in the intermediate state, the process on the reduction reducing the requirements of the complete degree, reduce the used as the reducing agent; the mixture with chemical separation, the product is very good use can be obtained. (by machine translation)

Extending the series of p-substituted tetrafluorobenzoic acids: synthesis, properties and structure

The synthesis of the derivatives of p-aminotetrafluorobenzoic acid, p-H2NC6F4CO2H (2b), by hydrolysis, acylation or interaction with aldehydes was developed giving H2NC6F4CO2K (2a), C6F5C(O)N(H)C6F4CO2Et (3) and (E)-ArCH[dbnd]NC6F4CO2Et (4–11). The chemical derivatization of tetrafluoroterephthalic acid, p-HO2CC6F4CO2H (12), by hydrolysis, etherification and reduction was performed giving a number of symmetrical X(O)CC6F4C(O)X (13–15; X?=?Cl, NEt2, OMe) or unsymmetrical YC6F4CO2Me (15a–b, 16, 18–21; Y?=?CO2K, CO2H, CH2OH, C(O)Cl, C(O)C6H3(i-Pr)2, CO2CH2C6F4CO2Me, CO2C6H4Bu-t), HOCH2C6F4CO2H (17), [MeO2CC6F4]2Y (22, 23; Y?=?OCH2CH2O, N(H)C6H4N(H)) compounds. All substances were thoroughly investigated by spectroscopic methods (multinuclear NMR and IR spectroscopy, mass-spectrometry). The molecular structures of p-H2NC6F4CO2Et (2) and p-HO2CC6F4CO2Me (15b) have been determined by X-ray diffraction analysis.

Preparation method of 2,3,5,6-tetrafluorohydrazine-1,4-benzene dimethanol

The invention discloses a preparation method of 2,3,5,6-tetrafluorohydrazine-1,4-benzene dimethanol, and belongs to the technical field of fine chemical synthesis. The preparation method is characterized by comprising the following reaction steps that (1) chlorine is led into paraxylene under catalyzing of a catalyst and irradiation of visible light to achieve chlorination, then nitrogen is led in to expel residual hydrogen chloride gas, and 1,4-dual(trichloromethyl)-2,3,5,6-tetrachlorobenzene is obtained; (2) the 1,4-dual(trichloromethyl)-2,3,5,6-tetrachlorobenzene and potassium fluoride are subject to fluorization and alcoholysis in an alcohol solvent, the solvent is recycled through reduced pressure distillation, washing is carried out the neutral state is obtained, drying is carried out, and 1,4-dual(silane oxygen methyl chloride)-2,3,5,6-tetrachlorobenzene is obtained; and (3) hydrogen is led into the 1,4-dual(silane oxygen methyl chloride)-2,3,5,6-tetrachlorobenzene in a solvent containing a metal catalyst and an acid-binding agent to be subject to catalytic hydrogenation reduction, an upper-layer organic phase is subject to cooling, suction filtration and drying to obtain the2,3,5,6-tetrafluorohydrazine-1,4-benzene dimethanol. The preparation method has the beneficial effects that the raw materials are low in price and easy to obtain, the synthetic route is short, operation is easy and convenient, and the product cost is low.