92339-07-6

Usage

InChI:InChI=1/C8H6F4O2/c9-5-3(1-13)6(10)8(12)4(2-14)7(5)11/h13-14H,1-2H2

Upstream product

• 719-32-4 tetrachloroterephthaloyl dichloride 
• 1786-85-2 2,3,5,6-tetrachloro-1,4-benzenecarboxamide 
• 19842-76-3 2,3,5,6-tetrafluorobenzaldehyde 
• 327-54-8 1,2,4,5-Tetrafluorobenzene 
• 652-36-8 2,3,5,6-tetrafluoroterephthalic acid 
• 123-91-1 1,4-dioxane 
• 7440-02-0 nickel 
• 95-50-1 1,2-dichloro-benzene 
• 3217-47-8 2,3,5,6-tetrafluoroterephthalaldehyde 
• 1634-04-4 tert-butyl methyl ether 
• 727-55-9 dimethyl 2,3,5,6-tetrafluoroterephthalate 
• 950-70-9 2,3,5,6-tetrafluoroterephthalic acid difluoride 
• 1242014-43-2 N,N,N',N'-tetrakis(tert-butoxycarbonyl)-(2,3,5,6-tetrafluoro benzene)-1,4-biscarboxamide 
• 106-42-3 para-xylene 

Downstream Products

• 776-40-9 α,α’-dibromo-m-tetrafluoroxylene 
• 83282-91-1 2,3,5,6-tetrafluoro-4-(methoxymethyl)benzyl alcohol 
• 79538-03-7 2,3,5,6-tetrafluoro-4-methylbenzyl alcohol 
• 703-87-7 1,4-dimethyl-2,3,5,6-tetrafluorobenzene 
• 99705-45-0 4-chloromethyl-2,3,5,6-tetrafluorobenzyl alcohol 
• 3217-47-8 2,3,5,6-tetrafluoroterephthalaldehyde 

Relevant academic research and scientific papers

A substituted aromatic alcohols of the economical efficiency of the synthesis process (by machine translation)

The invention discloses a substituted aromatic alcohols of the economical efficiency of the synthesis process, the COOR1 - C6 F4 - COOR1 (R1 Representative C1 - C4 Alkyl) to the organic solvent in the input, in the NaBH4 Under the action of the shall CH reduction reaction2 OH - C6 F4 - CH2 OH (II) and CH2 OH - C6 F4 - COOH (III); the mixture is dissolved in a weak acid buffer solution, after adjusting the pH of the extraction, the aqueous layer containing in II, III contained in the oil reservoir; the oil reservoir into the non-protic solvent removes the carboxyl, shall be CH2 OH - C6 HF4 . The present invention, reduction process residence in the intermediate state, the process on the reduction reducing the requirements of the complete degree, reduce the used as the reducing agent; the mixture with chemical separation, the product is very good use can be obtained. (by machine translation)

Synthesis method of 2,3,5,6-tetrafluoro-4-methoxymethyl benzyl alcohol

The invention discloses a method for synthesizing 2,3,5,6-tetrafluoro-4-methoxymethyl benzyl alcohol through 1,4-di(methoxymethyl)-2,3,5,6-tetrafluorobenzene and belongs to the technical field of organic synthesis. The method comprises the following steps: taking the 1,4-di(methoxymethyl)-2,3,5,6-tetrafluorobenzene to react in a mixed solution composed of a sulfuric acid water solution and organiccarboxylic acid; carrying out ester group hydrolysis reaction on an obtained mixture under the action of inorganic alkali; carrying out methylation reaction of hydroxyl under the action of the inorganic alkali; finally, separating and purifying to obtain the 2,3,5,6-tetrafluoro-4-methoxymethyl benzyl alcohol and recycling the 1,4-di(methoxymethyl)-2,3,5,6-tetrafluorobenzene. According to the method provided by the invention, resource utilization of the low-value 1,4-di(methoxymethyl)-2,3,5,6-tetrafluorobenzene is realized; meanwhile, the method has the advantages of cheap and easy-to-obtain reaction reagents, moderate reaction conditions, simplicity in operation, high synthesis yield, good product quality and the like, and has very high social and economic value.

Extending the series of p-substituted tetrafluorobenzoic acids: synthesis, properties and structure

The synthesis of the derivatives of p-aminotetrafluorobenzoic acid, p-H2NC6F4CO2H (2b), by hydrolysis, acylation or interaction with aldehydes was developed giving H2NC6F4CO2K (2a), C6F5C(O)N(H)C6F4CO2Et (3) and (E)-ArCH[dbnd]NC6F4CO2Et (4–11). The chemical derivatization of tetrafluoroterephthalic acid, p-HO2CC6F4CO2H (12), by hydrolysis, etherification and reduction was performed giving a number of symmetrical X(O)CC6F4C(O)X (13–15; X?=?Cl, NEt2, OMe) or unsymmetrical YC6F4CO2Me (15a–b, 16, 18–21; Y?=?CO2K, CO2H, CH2OH, C(O)Cl, C(O)C6H3(i-Pr)2, CO2CH2C6F4CO2Me, CO2C6H4Bu-t), HOCH2C6F4CO2H (17), [MeO2CC6F4]2Y (22, 23; Y?=?OCH2CH2O, N(H)C6H4N(H)) compounds. All substances were thoroughly investigated by spectroscopic methods (multinuclear NMR and IR spectroscopy, mass-spectrometry). The molecular structures of p-H2NC6F4CO2Et (2) and p-HO2CC6F4CO2Me (15b) have been determined by X-ray diffraction analysis.

Preparation method of 2,3,5,6-tetrafluorohydrazine-1,4-benzene dimethanol

The invention discloses a preparation method of 2,3,5,6-tetrafluorohydrazine-1,4-benzene dimethanol, and belongs to the technical field of fine chemical synthesis. The preparation method is characterized by comprising the following reaction steps that (1) chlorine is led into paraxylene under catalyzing of a catalyst and irradiation of visible light to achieve chlorination, then nitrogen is led in to expel residual hydrogen chloride gas, and 1,4-dual(trichloromethyl)-2,3,5,6-tetrachlorobenzene is obtained; (2) the 1,4-dual(trichloromethyl)-2,3,5,6-tetrachlorobenzene and potassium fluoride are subject to fluorization and alcoholysis in an alcohol solvent, the solvent is recycled through reduced pressure distillation, washing is carried out the neutral state is obtained, drying is carried out, and 1,4-dual(silane oxygen methyl chloride)-2,3,5,6-tetrachlorobenzene is obtained; and (3) hydrogen is led into the 1,4-dual(silane oxygen methyl chloride)-2,3,5,6-tetrachlorobenzene in a solvent containing a metal catalyst and an acid-binding agent to be subject to catalytic hydrogenation reduction, an upper-layer organic phase is subject to cooling, suction filtration and drying to obtain the2,3,5,6-tetrafluorohydrazine-1,4-benzene dimethanol. The preparation method has the beneficial effects that the raw materials are low in price and easy to obtain, the synthetic route is short, operation is easy and convenient, and the product cost is low.

Technology for preparing 2,3,5,6-tetrafluoro-1,4-benzenedimethanol

The invention discloses a technology for preparing 2,3,5,6-tetrafluoro-1,4-benzenedimethanol, and belongs to the technical field of fine chemical synthesis. The technology includes the following reaction steps that (1) dry hydrogen chloride gas is led into 2,3,5,6-tetrafluoro-1,4-terephthalonitrile in an ether solvent for reaction, then low carbon alcohol is added for reaction, and a solution of 2,3,5,6-tetrafluoro-1,4-imino-terephthalate is obtained; (2) the 2,3,5,6-tetrafluoro-1,4-imino-terephthalate is reacted with water, an organic phase substance is collected and washed with water to be neutral, the solvent is removed in a vacuum distillation mode, and 2,3,5,6-tetrafluoro-1,4-terephthalic acid diester is obtained; (3) the 2,3,5,6-tetrafluoro-1,4-terephthalic acid diester is subjected to a catalyzed hydrogeneration reduction reaction, an organic phase substance is collected, cooled, subjected to suction filtration and dried, and the 2,3,5,6-tetrafluoro-1,4-benzenedimethanol is obtained. The technology has the advantages that the raw materials are low in cost, operation is easy and convenient, and high-concentration acid wastewater is avoided.

Luminogenic and fluorogenic compounds and methods to detect molecules or conditions

A method to detect the presence or amount of at least one molecule in a sample which employs a derivative of luciferin or a derivative of a fluorophore is provided.

Introducing Solubility Control for Improved Organic P-Type Dopants

To overcome the poor solubility of the widely used p-type dopant 2,3,5,6-tetrafluoro-7,7,8,8-tetracyanoquinodimethane (F4TCNQ), we have synthesized a series of structure-modified, organic p-type dopants to include alkyl ester groups designed to enable solubility and miscibility control. UV-vis-NIR and cyclic voltammetry measurements show increased solubility of mono- and diester substituted dopants with only modest changes to acceptor strength. Using absorption spectroscopy, photoluminescence, and in-plane conductivity measurements, we demonstrate that the new dopants can successfully p-type dope poly(3-hexylthiophene-2,5-diyl) (P3HT). Monoester substituted dopants are characterized by only slightly reduced electron affinity relative to F4TCNQ, but greater doping effectiveness due to increased miscibility with P3HT. Diester substituted dopants undergo a dimerization reaction before assuming their doped states, which may help anchor dopants into position post deposition, thus decreasing the negative effect of dopant drift and diffusion. We conclude that increased dopant solubility/miscibility increases the overall effectiveness of doping in solution-cast polymer films and that ester modification is a practical approach to achieving solubility/miscibility control in TCNQ-type dopants (Figure Presented).

METHOD FOR PRODUCING ALCOHOL COMPOUND

A method for producing an alcohol compound, wherein a carboxylic acid ester compound is reduced with hydrogen in the presence of a ruthenium complex which is obtained by reacting an imidazolium salt (A) having at least one optionally substituted amino group with a ruthenium compound (B) in the presence of a base (C).

METHOD FOR PRODUCING ALCOHOL COMPOUND AND CATALYST THEREFOR

A method for producing an alcohol compound, wherein a carboxylic acid ester compound is reduced with hydrogen in the presence of a ruthenium complex which is obtained by reacting a pyridine compound having at least one optionally substituted amino group with a ruthenium compound.

METHOD FOR PRODUCING HALOGEN-SUBSTITUTED BENZENE DIMETHANOL

A method for producing a halogen-substituted benzene dimethanol, the method including: a first step of reacting a compound represented by formula (1) with a compound represented by formula (2) to obtain a dicarboxamide compound represented by formula (3), and a second step of reducing the dicarboxamide compound using a borohydride compound to obtain a halogen-substituted benzene dimethanol represented by formula (4).