83392-35-2

Upstream product

• 20365-21-3 methyl 3-oxo-3-phenylpropanedithioate 
• 122-00-9 para-methylacetophenone 
• 41467-27-0 3,3-bis(methylthio)-1-(p-tolyl)prop-2-en-1-one 
• 2314-48-9 (S,S)-dimethyl trithiocarbonate 
• 98-86-2 acetophenone 

Downstream Products

• 843640-84-6 ethyl 2-{[3-(4-methylphenyl)-3-oxopropanthioyl]amino}acetate 
• 1142124-74-0 5-methylmercaptothiocarbonyl-4-(4-chlorophenyl)-6-(4-methylphenyl)-3,4-dihydropyrimidin-2(1H)-one 
• 1142124-67-1 5-methylmercaptothiocarbonyl-4-phenyl-6-(4-methyl-phenyl)-3,4-dihydropyrimidin-2(1H)-one 
• 1142124-71-7 5-methylmercaptothiocarbonyl-4-(4-methoxyphenyl)-6-(4-methylphenyl)-3,4-dihydropyrimidin-2(1H)-one 
• 1142124-89-7 3-(4-methylbenzoyl)-2H-chromene-2-thione 
• 1228956-78-2 3-(4-methylbenzoyl)-8-methoxy-2H-chromene-2-thione 
• 1263317-24-3 (3-thioxo-3H-benzo[f]chromen-2-yl)(p-tolyl)methanone 
• 1448887-68-0 4-(4-methoxyphenyl)-3-(4-methylbenzoyl)-2-methylsulfanyl-6-pyrrolidino-5,6-dihydro-4H-thiopyran 
• 3837-95-4 1-(p-tolyl)but-2-en-1-one 
• 1454846-25-3 3-hydroxy-3-p-tolylhex-5-enedithioic acid methyl ester 
• 1357511-81-9 C₂₂H₂₀BrNO₃S₂ 
• 1357513-73-5 C₂₃H₂₃NO₃S₂ 
• 1357509-24-0 C₂₁H₁₇N₃O₃S₂ 
• 1592508-07-0 5-(methylthio)-3-(p-tolyl)-1H-pyrazole 

Relevant academic research and scientific papers

Silica-ZnCl2: An efficient and reusable solid catalyst for one pot synthesis of 5-methyl mercaptothiocarbonyl-4-aryl-3- dihydropyrimidin-2(1H)-ones under solvent-free conditions

Synthetic application of Silica-ZnCl2, as an efficient and eco-friendly catalyst for the synthesis of a small library of dihydropyrimidinones is described in this report. The reaction involves a one pot, multicomponent reaction of β-oxodithioca

Facile route to highly functionalized 2H-chromene-2-thiones via ring annulations of β-oxodithioesters with phenols catalyzed by AlCl3 under solvent-free conditions

A facile synthesis of chromene-2-thiones by the Pechmann condensation of phenols and β-oxodithioesters catalyzed by AlCl3 under solvent-free condition has been reported. The best results were obtained in the case of substituted phenols such as

An efficient transesterification of β-oxodithioesters catalyzed by stannous chloride under solvent-free conditions

Transesterification of β-oxodithioesters catalyzed by stannous chloride under solvent-free condition has been reported for the first time. The short reaction time and good to excellent yields using inexpensive catalysts are attractive features of this synthetic protocol. Copyright

4-Dimethylamino pyridine-promoted one-pot three-component regioselective synthesis of highly functionalized 4 H -thiopyrans via heteroannulation of β-oxodithioesters

A highly convergent and regioselective heteroannulation protocol for the synthesis of hitherto unreported highly substituted 2-amino-4-(aryl/alkyl)-5- (aroyl/heteroaroyl)-3-(cyano/carboalkoxy)-6-methylthio-4H-thiopyran derivatives has been developed. This

Molecular docking and in vitro antileishmanial evaluation of chromene-2-thione analogues

Leishmaniases are an epidemic in various countries, and the parasite is developing resistance against available drugs. Thus, development of new drugs against Leishmania is an open area of investigation for synthetic organic chemists. To meet this challeng

Novel 3-alkanoyl/aroyl/heteroaroyl-2H-chromene-2-thiones: Synthesis and evaluation of their antioxidant activities

A facile, convenient and high yielding synthesis of a combinatorial library of 3-alkanoyl/aroyl/heteroaroyl-2H-chromene-2-thiones has been developed by the condensation of easily accessible β-oxodithioesters and salicylaldehyde/substituted 2-hydroxybenzal

Application of β-Oxodithioesters in domino and multicomponent reactions: Facile route to dihydropyrimidines and coumarins

A facile route to hitherto unknown 5-methylmercaptothiocarbonyl-4-aryl-3,4- dihydropyrimidin-2(1H)-ones and substituted 2H-chromene-2-thiones has been developed. SnCl2catalyzed cyclocondensation of β-oxodithioesters with a variety of readily ac

A facile method for the synthesis of substituted 2-ylidene-1,3-oxathioles from acetophenones

Compounds incorporating 1,3-oxathiole moieties in their frameworks are biologically active. Active methylene ketones can be easily converted to the corresponding dithiocarboxylates by treatment with trithiocarbonate in the presence of sodium hydride. The

An efficient synthesis of highly substituted pyrroles from β-oxodithiocarboxylates

α-Oxoketene-N,S-acetals, prepared by the reaction of alkyl glycinate hydrochlorides with β-oxodithiocarboxylates followed by alkylation, underwent cyclization in presence of chloromethyleneiminium salt derived from POCl3/DMF to afford alkyl-3-a

A METHOD FOR PRODUCING DIVERSE SET OF DITHIOATE COMPOUNDS

The present invention relates to a method of preparing combinatorail library of alkyl-β-oxodithioates of general formulae 7 to 10, from carbonyl compounds containing active methylene group and methyldithoate imidazoles of formula 1 or 2, which form the ba