16715-75-6

Basic information

• Product Name: 2-(4-methylphenyl)-5-chlorobenzoxazole
• Synonyms: 2-(4-methylphenyl)-5-chlorobenzoxazole
• CAS NO: 16715-75-6
• Molecular Weight: 243.692
• Mol File: 16715-75-6.mol
• Article Data: 32

Chemical Properties

• CAS DataBase Reference: 2-(4-methylphenyl)-5-chlorobenzoxazole(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(4-methylphenyl)-5-chlorobenzoxazole(16715-75-6)
• EPA Substance Registry System: 2-(4-methylphenyl)-5-chlorobenzoxazole(16715-75-6)

Safety Data

• Hazardous Substances Data: 16715-75-6(Hazardous Substances Data)

Upstream product

• 93099-44-6 4-chloro-2-nitrophenyl 4-methylbenzylether 
• 104-87-0 4-methyl-benzaldehyde 
• 95-85-2 2-hydroxy-5-chloro-aniline 
• 874-60-2 4-methyl-benzoyl chloride 
• 104-84-7 para-methylbenzylamine 
• 1139705-26-2 4-methylphenyl imidazolesulfonate 
• 17200-29-2 5-chloro-benzoxazole 
• 16308-16-0 1-(diacetoxyiodo)-4-methylbenzene 
• 1576-35-8 toluene-4-sulfonic acid hydrazide 
• 98-59-9 p-toluenesulfonyl chloride 
• 5720-05-8 4-methylphenylboronic acid 
• 624-31-7 4-tolyl iodide 
• 13939-06-5 molybdenum hexacarbonyl 
• 695-96-5 2-bromo-4-chlorophenol 

Downstream Products

• 53349-54-5 5-chloro-2-{4-[trans-2-(2-phenyl-benzofuran-6-yl)-vinyl]-phenyl}-benzooxazole 
• 37421-71-9 2-{4-[4-(5-chloro-benzooxazol-2-yl)-trans-styryl]-phenyl}-7-phenyl-2,7-dihydro-benzo[1,2-d;3,4-d']bis[1,2,3]triazole 
• 53415-39-7 5-chloro-2-[4-(4-trans-styryl-trans-styryl)-phenyl]-benzooxazole 
• 59136-16-2 5-chloro-2-{4-[2-(2-phenyl-2H-[1,2,3]triazol-4-yl)-vinyl]-phenyl}-benzooxazole 
• 65204-13-9 5-chloro-2-{4-[4-(4-phenyl-[1,2,3]triazol-2-yl)-styryl]-phenyl}-benzooxazole 
• 59099-05-7 5-chloro-2-{4-[4-(2-phenyl-2H-[1,2,3]triazol-4-yl)-styryl]-phenyl}-benzooxazole 
• 65204-30-0 5-chloro-2-{4-[4-(4,5-diphenyl-[1,2,3]triazol-2-yl)-styryl]-phenyl}-benzooxazole 
• 65204-04-8 5-chloro-2-{4-[4-(2,5-diphenyl-2H-[1,2,3]triazol-4-yl)-styryl]-phenyl}-benzooxazole 
• 65204-19-5 5-chloro-2-{4-[4-(4-chloro-5-phenyl-[1,2,3]triazol-2-yl)-styryl]-phenyl}-benzooxazole 
• 59098-30-5 5-chloro-2-{4-[2-(5-methyl-2-phenyl-2H-[1,2,3]triazol-4-yl)-vinyl]-phenyl}-benzooxazole 

Relevant articles and documents

Iron(III) Chloride Mediated para-Selective C-H Functionalization: Access to C5-Chloro and C5,C7-Dichloro/Dianisyl Substituted 2-Arylbenzoxazoles

Iron(III) chloride mediated para-selective C?H chlorination and subsequent annulation of 2-amidophenol to synthesize C5- and C5, C7-chlorinated benzoxazoles was developed. Further, the oxidative cross-dehydrogenative coupling of amidophenol with anisole b

Pyrazole-3-carboxylates assisted N-heterocyclic carbene palladium complexes: synthesis, characterization, and catalytic activities towards arylation of azoles with arylsulfonyl hydrazides

Four mononuclear and dinuclear pyrazole-3-carboxylates assisted NHC–Pd complexes have been synthesized and characterized. Notably, the bridge-cleavage reactions of [Pd(μ-Cl)(Cl)(NHC)]2 with 1H-pyrazole-3-carboxylic acid afforded dinuclear complexes [(NHC)Pd(μ-1H-pyrazolato-3-carboxylate)]2, in which the 1H-pyrazolato-3-carboxylate was employed as a N^N^O dianionic chelating and bridging ligand. To further explore the structural features and catalytic properties of the complexes, 1-methyl-1H-pyrazole-3-carboxylic acid was introduced into the coordination with [Pd(μ-Cl)(Cl)(NHC)]2 and the corresponding mononuclear complexes (NHC)PdCl(1-methyl-1H-pyrazole-3-carboxylate) were obtained. The catalytic properties of the complexes in desulfitative arylation of azoles with arylsulfonyl hydrazides were initially investigated.

Straightforward synthesis of benzoxazoles and benzothiazoles via photocatalytic radical cyclization of 2-substituted anilines with aldehydes

Eosin Y-catalyzed one-pot coupling and cyclization of o-substituted anilines with aldehydes to form benzoxazoles and benzothiazoles under mild condition has been developed. The reaction scope was broadly tolerant of various 2-substituted anilines and aldehydes. The desired products were obtained in high yields with the use of eosin Y as a photocatalyst under a substantial refinement of reaction conditions in comparison with previous literature. Based on the experimental results observed, a plausible mechanism involving a radical process has been proposed.