83410-18-8

Basic information

• Product Name: 5-IODO-6-METHYL-4-PYRIMIDINAMINE
• Synonyms: 5-IODO-6-METHYL-4-PYRIMIDINAMINE;5-IODO-6-METHYL-4-PYRIMIDINYLAMINE;5-Iodo-6-MethylpyriMidin-4-aMine;4-PyriMidinaMine, 5-iodo-6-Methyl-
• CAS NO: 83410-18-8
• Molecular Formula: C₅H₆IN₃
• Molecular Weight: 235.03
• Mol File: 83410-18-8.mol

Chemical Properties

• Boiling Point: 318.7 °C at 760 mmHg
• Flash Point: 146.6 °C
• Appearance: /
• Density: 2.017 g/cm³
• Vapor Pressure: 0.000354mmHg at 25°C
• Refractive Index: 1.687
• Storage Temp.: Keep in dark place,Inert atmosphere,Room temperature
• CAS DataBase Reference: 5-IODO-6-METHYL-4-PYRIMIDINAMINE(CAS DataBase Reference)
• NIST Chemistry Reference: 5-IODO-6-METHYL-4-PYRIMIDINAMINE(83410-18-8)
• EPA Substance Registry System: 5-IODO-6-METHYL-4-PYRIMIDINAMINE(83410-18-8)

Safety Data

• Hazardous Substances Data: 83410-18-8(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Industry:
5-IODO-6-METHYL-4-PYRIMIDINAMINE is used as a chemical intermediate for the synthesis of various pharmaceuticals, leveraging its biological activities to contribute to the development of new drugs.
Used in Agrochemical Industry:
In the agrochemical sector, 5-IODO-6-METHYL-4-PYRIMIDINAMINE is employed as an intermediate in the production of agrochemicals, potentially enhancing crop protection and management through its incorporation into effective compounds.
Used in Research and Development:
5-IODO-6-METHYL-4-PYRIMIDINAMINE is utilized in research and development settings for studying its anti-cancer and anti-inflammatory properties, exploring its potential in treating certain diseases and disorders, and advancing the understanding of its biological effects.
Used in Drug Formulation:
5-IODO-6-METHYL-4-PYRIMIDINAMINE may also be used in drug formulation processes, where its specific properties can be harnessed to improve the efficacy and targeting of therapeutic agents in medicine.

InChI:InChI=1/C5H6IN3/c1-3-4(6)5(7)9-2-8-3/h2H,1H3,(H2,7,8,9)

Upstream product

• 108260-15-7 2-(iodomethyl)-6-methyl-4-pyrimidinylamine 
• 108260-17-9 4-Amino-2-diiodmethyl-6-methyl-pyrimidin 
• 7752-74-1 5-iodo-6-methyl-3H-pyrimidin-4-one 
• 83410-15-5 4-chloro-5-iodo-6-methyl-pyrimidine 
• 461-98-3 4-amino-2,6-dimethylpyrimidine 
• 3435-28-7 6-methylpyrimidin-4-ylamine 

Downstream Products

• 1206631-23-3 ethyl 5-(6-methyl-5-{[4-(trifluoromethyl)phenyl]ethynyl}pyrimidin-4-ylaminomethyl)-2-furancarboxylate 
• 1207324-42-2 4-amino-6-methyl-5-{[4-(trifluoromethyl)phenyl]ethynyl}pyrimidine 

Relevant articles and documents

AGRICULTURAL CHEMICALS

The present invention relates to benzimidazole and benzotriazole compounds which are of use in the field of agriculture as fungicides.

Studies on the Regioselective Halogenation of 4-Amino-2-iodomethyl-6-methylpyrimidines

In the presence of oxidants, 4-amino-2-iodomethyl-6-methylpyrimidines 2 undergo regioselective reactions in the position 2 and/or 5.Thus, the reaction of 2a with hydrogen peroxide proceeds under dealkylation and iodination to give 4-amino-5-iodo-6-methylpyrimidine 7.Depending on reaction temperature and molar ratios the reaction of 2a with bromine or chlorine leads to the corresponding 4-amino-5-halogeno-2-halogenomethyl-6-methylpyrimidines 2c, 9a and 9d.The 5-substituted pyrimidines 2b, c afford the 2-bromo (or chloro) methyl derivatives 9b, c.