83465-82-1

Basic information

• Product Name: 2-(3,5-dimethylbenzoyl)aniline
• Synonyms: 2-(3,5-dimethylbenzoyl)aniline;(2-Aminophenyl)(3,5-dimethylphenyl)methanone
• CAS NO: 83465-82-1
• Molecular Formula: C₁₅H₁₅NO
• Molecular Weight: 225.2857
• Mol File: 83465-82-1.mol
• Article Data: 10

Chemical Properties

• Appearance: /
• Storage Temp.: 2-8°C
• CAS DataBase Reference: 2-(3,5-dimethylbenzoyl)aniline(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(3,5-dimethylbenzoyl)aniline(83465-82-1)
• EPA Substance Registry System: 2-(3,5-dimethylbenzoyl)aniline(83465-82-1)

Safety Data

• Hazardous Substances Data: 83465-82-1(Hazardous Substances Data)

Usage

General Description

2-(3,5-dimethylbenzoyl)aniline is a chemical compound that belongs to the class of aromatic organic compounds. It is used in the synthesis and production of various pharmaceuticals, dyes, and organic products. This chemical is known for its unique chemical structure, containing both benzene and aniline groups, which makes it useful for a variety of applications. The compound is also used as a reagent in organic chemistry and is commonly used in research and laboratory settings for its synthetic and analytical properties. Additionally, it is known for its role in the production of fluorescent materials and as a building block in the creation of new chemical compounds. Overall, 2-(3,5-dimethylbenzoyl)aniline plays an important role in the chemical and pharmaceutical industries due to its versatile properties and applications.

Upstream product

• 525-76-8 2-methyl-4-oxo-3,1-benzoxazine 
• 556-96-7 5-bromo-1,3-xylene 
• 1885-29-6 anthranilic acid nitrile 
• 207976-79-2 N-(2-(3,5-dimethylbenzoyl)phenyl)acetamide 
• 34696-73-6 3,5-dimethyphenylmagnesium bromide 
• 133776-41-7 anthranilic acid N-methoxy-N-methylamide 
• 118-92-3 anthranilic acid 

Downstream Products

• 1025506-22-2 4-(3,5-dimethylphenyl)-2,1,3-benzothiadiazine 2,2-dioxide 
• 890658-75-0 4-(3',5'-dimethylphenyl)-2-methylquinoline 
• 951884-33-6 3,5-dimethylphenyl 2-iodophenyl ketone 
• 103021-74-5 2,4-dimethyl-9-phenylfluoren-9-ol 
• 103021-73-4 9-(3,5-dimethylphenyl)fluoren-9-ol 
• 713517-60-3 5-(3,5-dimethyl-phenyl)-1-(4-methoxy-benzyl)-1,3-dihydro-benzo[e][1,4]diazepin-2-one 
• 103021-66-5 2-amino-3',5'-dimethyltriphenylmethanol 

Relevant articles and documents

Novel transformation of aryl 2-iodophenyl ketones into 1,3-diarylisoquinolines with (TMS)2NH, styrenes, NIS, and tBuOK

Treatment of aryl 2-iodophenyl ketones with TMS2NH in the presence of Sc(OTf)3 at warming conditions, followed by the reaction with styrenes and NIS gave N-(1-aryl-2-iodoethyl) aryl 2-iodophenyl ketimines. Further treatment of N-(1-aryl-2-iodoethyl) aryl 2-iodophenyl ketimines with tBuOK in the presence of 1,10-phenanthroline at 120 °C generated 1,3-diarylisoquinolines in moderate yields through SET from tBuOK onto the iodophenyl group to form aryl radicals, their 6-endo-trig cyclization onto the vinyl groups, and aromatization of the cyclized intermediates. The present method is a novel approach for the preparation of the isoquinoline core via two steps from aryl 2-iodophenyl ketones.

Method for synthesizing ortho-amino aromatic ketone from aromatic carboxylic acid

Disclosed is a method for synthesizing ortho-amino aromatic ketone from aromatic carboxylic acid. The method comprises the steps that with 2-arylsulfonamido aromatic carboxylic acid shown in the description as a raw material and triphenylphosphine as a deoxidizer, under the illumination of blue light, in a 1,4-dioxane solution, under an argon atmosphere, in the presence of the dipotassium hydrogenphosphate, with [Ir(dF(CF3)ppy)2(dtbbpy)]PF6 as a photocatalyst, the ortho-amino aromatic ketone compound is obtained; the structure of the photocatalyst [Ir(dF(CF3)ppy)2(dtbbpy)]PF6 is shown in thedescription.

Synthesis of Diiodinated All-Carbon 3,3′-Diphenyl-1,1′-spirobiindene Derivatives via Cascade Enyne Cyclization and Electrophilic Aromatic Substitution

A synthetic method for the construction of diiodinated all-carbon spirobiindene derivatives has been developed from the reaction of propargyl alcohol-tethered alkylidenecyclopropanes with iodine. The reaction proceeded through an iodination-initiated cascade intramolecular enyne cyclization and electrophilic aromatic substitution reaction process in 1,2-dichloroethane upon heating, giving desired spirocyclic products in moderate to excellent yields. Further transformation of the obtained products has also been presented.