83529-41-3Relevant academic research and scientific papers
Phosphonylation of 1,3-diaryl-2,3-dihydro-1H-naphth[1,2-e][1,3]oxazine by dialkyl and diaryl phosphonates
Metlushka, Kirill E.,Alfonsov, Vladimir A.,McKenna, Charles E.,Kashemirov, Boris A.,Kataeva, Olga N.,Zheltukhin, Viktor F.,Sadkova, Dilyara N.,Dobrynin, Alexey B.
, p. 2645 - 2646 (2008)
The possibility of using of easily available 1-(α-aminobenzyl)-2- naphthols as chiral auxiliaries in the synthesis of non-racemic α-aminophosphonates has been shown. Copyright Taylor & Francis Group, LLC.
N,N'-Dibenzyl-N,N'-ethylenetartramide: A Rationally Designed Chiral Auxiliary for the Allylboration Reaction
Roush, William R.,Banfi, Luca
, p. 3979 - 3982 (2007/10/02)
The chiral auxiliary designated in the title was designed as a probe of our previously suggested mechnism of asymmetric induction with tartrate allylboronates 1-3, namely that n/n electronic repulsive interactions between electron pairs on the aldehydic oxygen atom and an ester carbonyl disfavor transition-state C relative to A.The results reported for the new reagent 5 strongly support this thesis and suggest that the convergence of functional groups toward a metal center can be an exceedingly useful strategy for achieving a topological bias in the enantioselective functionalization of a carbonyl group.
