83664-33-9

Basic information

• Product Name: 2-BENZYLOXY-5-BROMOPYRIDINE
• Synonyms: 2-BENZYLOXY-5-BROMOPYRIDINE;5-BROMO-2-BENZYLOXYPYRIDINE;5-bromo-2-(phenylmethoxy)pyridine;6-Benzyloxy-3-bromopyridine
• CAS NO: 83664-33-9
• Molecular Formula: C₁₂H₁₀BrNO
• Molecular Weight: 264.1179
• Product Categories: blocks;Bromides;Pyridines
• Mol File: 83664-33-9.mol
• Article Data: 35

Chemical Properties

• Melting Point: 45-48°C
• Boiling Point: 331.248 °C at 760 mmHg
• Flash Point: 154.133 °C
• Appearance: /
• Density: 1.439
• Vapor Pressure: 0mmHg at 25°C
• Refractive Index: 1.605
• Storage Temp.: Sealed in dry,Room Temperature
• PKA: 1.56±0.22(Predicted)
• CAS DataBase Reference: 2-BENZYLOXY-5-BROMOPYRIDINE(CAS DataBase Reference)
• NIST Chemistry Reference: 2-BENZYLOXY-5-BROMOPYRIDINE(83664-33-9)
• EPA Substance Registry System: 2-BENZYLOXY-5-BROMOPYRIDINE(83664-33-9)

Safety Data

• Hazardous Substances Data: 83664-33-9(Hazardous Substances Data)

Usage

General Description

2-BENZYLOXY-5-BROMOPYRIDINE is a chemical compound with the molecular formula C12H10BrNO that is commonly used in various chemical and pharmaceutical applications. It consists of a pyridine ring substituted with a bromine atom at the 5-position and a benzyloxy group at the 2-position. 2-BENZYLOXY-5-BROMOPYRIDINE is often used as a building block in the synthesis of pharmaceutical drugs and organic compounds. It has also been studied for its potential biological and pharmacological properties, particularly as an intermediate in the production of active pharmaceutical ingredients. Additionally, 2-BENZYLOXY-5-BROMOPYRIDINE may be used as a reagent in chemical reactions and as a reference standard in analytical chemistry.

InChI:InChI=1/C12H10BrNO/c13-11-6-7-12(14-8-11)15-9-10-4-2-1-3-5-10/h1-8H,9H2

Upstream product

• 624-28-2 2,5-dibromopyridine 
• 13466-38-1 5-bromopyridin-2(1H)-one 
• 100-44-7 benzyl chloride 
• 100-39-0 benzyl bromide 
• 53939-30-3 5-bromo-2-chloropyridine 
• 100-51-6 benzyl alcohol 
• 13472-85-0 2-methoxy-5-bromopyridine 
• 766-11-0 5-bromo-2-fluoropyridine 
• 39856-50-3 5-bromo2-nitropyridine 
• 13466-38-1 5-bromopyridin-2-ol 

Downstream Products

• 856849-02-0 2-benzyloxy-5-bromo-pyridine-1-oxide 
• 106154-28-3 6-Benzyloxy-4'H-[3,4']bipyridinyl-1'-carboxylic acid ethyl ester 
• 307498-10-8 2-benzyloxy-5-diphenylphosphanyl-pyridine 
• 83664-31-7 3β-(benzyloxy)-17β-<2-hydroxy-5-pyridyl>-5β-androst-14-ene 
• 83664-30-6 3β-(benzyloxy)-15β-hydroxy-17β-<2-hydroxy-5-pyridyl>-5β-androstane 
• 83664-29-3 3β-(benzyloxy)-15β-hydroxy-17-<2-(benzyloxy)-5-pyridyl>-5β-androst-16-ene 
• 83664-28-2 3β-(benzyloxy)-17β-acetoxy-17α-<2-(benzyloxy)-5-pyridyl>-5β-androst-15-ene 
• 1046143-60-5 5-benzyl-2-(benzyloxy)pyridine 
• 40864-08-2 2-benzyloxypyridine 
• 209974-01-6 2-Benzyloxy-5-[(3aS,4S,6R,6aR)-6-(tert-butyl-diphenyl-silanyloxymethyl)-2,2-dimethyl-tetrahydro-furo[3,4-d][1,3]dioxol-4-yl]-pyridine 
• 188871-69-4 2-Benzyloxy-5-((2S,3S,4R,5R)-3,4-bis-benzyloxy-5-benzyloxymethyl-tetrahydro-furan-2-yl)-pyridine 
• 188871-58-1 (2S,3R,4S,5R)-2-(6-Benzyloxy-pyridin-3-yl)-5-hydroxymethyl-tetrahydro-furan-3,4-diol 
• 307498-13-1 (2-oxo-1,2-dihydro-5-pyridyl)diphenylphosphine 

Relevant articles and documents

PIPERIDIN-1- YL-N-PYRYDI NE-3-YL-2-OXOACET AM IDE DERIVATIVES USEFUL FOR THE TREATMENT OF MTAP-DEFICIENT AND/OR MT A-ACCUMULATING CANCERS

Compounds are provided according to Formula (I) and pharmaceutically acceptable salts thereof, and pharmaceutical compositions thereof; wherein R1, R2, R3, R4, R6, R7, R8 and n are as defined herein. Compounds of the present invention are contemplated useful for the prevention and treatment of a variety of conditions.

SMALL MOLECULE INHIBITORS OF NF-kB INDUCING KINASE

The present invention relates to compounds that inhibit NIK and pharmaceutical compositions comprising such compounds and methods of using the same. These compounds and pharmaceutical compositions are envisaged to be useful for preventing or treating diseases such as cancer (such as B-cell malignancies including leukemias, lymphomas and myeloma), inflammatory disorders, autoimmune disorders, immunodermatologic disorders such as palmoplantar pustulosis and hidradenitis suppurativa, and metabolic disorders such as obesity and diabetes.

ION CHANNEL MODULATORS

The present invention is directed to, in part, fused heteroaryl compounds and compositions useful for preventing and/or treating a disease or condition relating to aberrant function of a voltage-gated, sodium ion channel, for example, abnormal late/persistent sodium current. Methods of treating a disease or condition relating to aberrant function of a sodium ion channel including neurological disorders (e.g., Dravet syndrome, epilepsy), pain, and neuromuscular disorders are also provided herein.