83824-80-0

Basic information

• Product Name: benzyl (2S)-1-benzyloxycarbonyl-aziridine-2-carboxylate
• Synonyms: benzyl (2S)-1-benzyloxycarbonyl-aziridine-2-carboxylate
• CAS NO: 83824-80-0
• Molecular Weight: 311.337
• Mol File: 83824-80-0.mol

Chemical Properties

• CAS DataBase Reference: benzyl (2S)-1-benzyloxycarbonyl-aziridine-2-carboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: benzyl (2S)-1-benzyloxycarbonyl-aziridine-2-carboxylate(83824-80-0)
• EPA Substance Registry System: benzyl (2S)-1-benzyloxycarbonyl-aziridine-2-carboxylate(83824-80-0)

Safety Data

• Hazardous Substances Data: 83824-80-0(Hazardous Substances Data)

Upstream product

• 67413-25-6 benzyl (-)-(2S)-1-trityl-aziridine-2-carboxylate 
• 501-53-1 benzyl chloroformate 
• 67413-26-7 L-aziridine-2-carboxylic acid benzyl ester 
• 60022-62-0 L-serine benzyl ester hydrochloride 
• 67553-36-0 benzyl 3-hydroxy-2-(tritylamino)propanoate 

Downstream Products

• 126496-85-3 (S)-2-Benzyloxycarbonylamino-3-(4-methoxy-1H-indol-3-yl)-propionic acid benzyl ester 
• 126496-82-0 (S)-2-Benzyloxycarbonylamino-3-(5-methyl-1H-indol-3-yl)-propionic acid benzyl ester 
• 106825-78-9 N-benzyloxycarbonyl-O-(2-chloroethyl)-L-serine benzyl ester 
• 669089-95-6 (S)-2-Benzyloxycarbonylamino-3-((2R,3S,4R,5S,6R)-3,4,5-triacetoxy-6-acetoxymethyl-tetrahydro-pyran-2-ylmethoxy)-propionic acid benzyl ester 
• 1170714-33-6 Nα-benzyloxycarbonyl-3-O-[1,5-anhydro-6-O-tert-butyldiphenylsilyl-3,4-O-isopropylidene-D-galactitol-2-yl]-L-serine benzyl ester 
• 64957-09-1 N,N'-bis(benzyloxycarbonyl)-L-cystine dibenzyl ester 
• 20806-43-3 Z-Ser(Bzl)-OH 
• 83824-85-5 (S)-2-Benzyloxycarbonylamino-3-cyclohexyloxy-propionic acid benzyl ester 
• 20700-93-0 Z-Ser(O-t-Bu)-OBn 
• 83824-86-6 (S)-3-Benzyloxy-2-benzyloxycarbonylamino-propionic acid benzyl ester 
• 83824-83-3 (S)-2-Benzyloxycarbonylamino-3-isopropoxy-propionic acid benzyl ester 
• 16214-42-9 N-benzyloxycarbonyl-S-benzyl-L-cysteine benzyl ester 

Relevant articles and documents

Genetic encoding of 2-aryl-5-carboxytetrazole-based protein photo-cross-linkers

Three γ-heteroatom-substituted N-methylpyrroletetrazole-lysines (mPyTXKs) were synthesized and subsequently incorporated into proteins site-specifically via genetic code expansion. The γ-seleno-substituted derivative, mPyTSeK, showed excellent incorporati

Aziridine ring opening as regio- and stereoselective access to O-glycosyl amino acids and their transformation into O-glycopeptide mimetics

Glycosyl amino acid mimetics of the typical GalNAc-(1→O)-Ser/Thr motif of O-glycopeptides were synthesised. Starting from galactose a 1,5-anhydro derivative could be obtained and regio- and stereoselectively coupled to serine- or threonine-derived aziridine compounds, respectively. The corresponding Fmoc derivatives could be used to prepare two 13-mer glycopeptides of the mucin MUC1 carrying instead of Ser-2 or Th-5, the corresponding O-glcycosyl amino acid mimetics.

CONSTRUCTION OF OPTICALLY PURE TRYPTOPHANS FROM SERINE DERIVED AZIRIDINE-2-CARBOXYLATES

The possibility of preparing optically pure tryptophan derivatives from various substituted indoles and (2R)- or (2S)-2-aziridinecarboxylates has been examined.Zinc triflate was found to be the only Lewis acid capable of bringing about this reaction in mo

Studies on 2-Aziridinecarboxylic Acid. IX. Convenient Synthesis of Optically Active S-Alkylcysteine, threo-S-Alkyl-β-methylcysteine, and Lanthionine Derivatives via the Ring-opening Reaction of Aziridine by Several Thiols

A convenient synthesis of optically active S-alkylcysteine, threo-S-alkyl-β-methylcysteine, and lanthionine derivatives has been investigated.Benzyl 1-benzyloxycarbonyl-(2S)-2-aziridinecarboxylate and benzyl (2S,3S)-1-benzyloxycarbonyl-3-methyl-2-aziridin

Studies on 2-Aziridinecarboxylic Acid. VI. Synthesis of β-Alkoxy-α-Amino Acids via Ring-opening Reaction of Aziridine

The reaction of aziridine derivatives having a urethane-type protecting group with several alcohols in the presence of boron trifluoride etherate afford the corresponding optically pure O-alkylserine and O-alkylthreonine derivatives via a ring-opening reaction of aziridine in good yield.