839678-00-1

Basic information

• Product Name: {[2-(4-bromo-phenyl)-1-(4-chloro-phenylcarbamoyl)-1-methyl-ethylcarbamoyl]-methyl}-carbamic acid tert-butyl ester
• Synonyms: {[2-(4-bromo-phenyl)-1-(4-chloro-phenylcarbamoyl)-1-methyl-ethylcarbamoyl]-methyl}-carbamic acid tert-butyl ester
• CAS NO: 839678-00-1
• Molecular Weight: 524.842
• Mol File: 839678-00-1.mol

Chemical Properties

• CAS DataBase Reference: {[2-(4-bromo-phenyl)-1-(4-chloro-phenylcarbamoyl)-1-methyl-ethylcarbamoyl]-methyl}-carbamic acid tert-butyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: {[2-(4-bromo-phenyl)-1-(4-chloro-phenylcarbamoyl)-1-methyl-ethylcarbamoyl]-methyl}-carbamic acid tert-butyl ester(839678-00-1)
• EPA Substance Registry System: {[2-(4-bromo-phenyl)-1-(4-chloro-phenylcarbamoyl)-1-methyl-ethylcarbamoyl]-methyl}-carbamic acid tert-butyl ester(839678-00-1)

Safety Data

• Hazardous Substances Data: 839678-00-1(Hazardous Substances Data)

Upstream product

• 4530-20-5 BOC-glycine 
• 839677-97-3 2-amino-3-(4-bromo-phenyl)-N-(4-chloro-phenyl)-2-methyl-propionamide 
• 589-15-1 1-bromomethyl-4-bromobenzene 
• 839677-94-0 (2R,5R)-5-(4-Bromo-benzyl)-2-tert-butyl-3-(4-chloro-phenyl)-5-methyl-1-(2,2,2-trifluoro-acetyl)-imidazolidin-4-one 

Relevant articles and documents

A practical synthesis of highly functionalized fused 1,6-dihydroimidazo-[1, 2-a]imidazole-2,5-diones, key intermediates for LFA-1 inhibitors

An alternative and chromatography-free approach for synthesis of a new class of LFA-1 inhibitors was developed. A key feature of this process involved a transformation of thioureas 14 to acyclic guanidine derivatives 9 followed by intramolecular cyclizati