84044-04-2

Basic information

• Product Name: Phosphonic acid, (aminophenylmethyl)-, diphenyl ester
• CAS NO: 84044-04-2
• Molecular Formula: C19H18NO3P
• Molecular Weight: 339.331
• Mol File: 84044-04-2.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: Phosphonic acid, (aminophenylmethyl)-, diphenyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Phosphonic acid, (aminophenylmethyl)-, diphenyl ester(84044-04-2)
• EPA Substance Registry System: Phosphonic acid, (aminophenylmethyl)-, diphenyl ester(84044-04-2)

Safety Data

• Hazardous Substances Data: 84044-04-2(Hazardous Substances Data)

Upstream product

• 106787-27-3 diphenyl α-aminobenzylphosphonate hydrobromide 
• 871315-40-1 C₂₆H₂₂NO₃P 
• 92-29-5 hydrobenzamide 
• 100-52-7 benzaldehyde 
• 65164-84-3 O,O-diphenyl {[(benzyloxy)carbonyl]amino}(phenyl)methylphosphonate 

Downstream Products

• 1584736-46-8 diphenyl ((4R,5R)-4,5-diphenyl-2-thioxooxazolidin-4-yl)phosphonate 
• 1584736-70-8 diphenyl ((4R,5R)-4-phenyl-2-thioxo-5-(m-tolyl)-1-tosylimidazolidin-4-yl)phosphonate 
• 1584736-71-9 diphenyl ((4R,5R)-4-phenyl-2-thioxo-5-(o-tolyl)-1-tosylimidazolidin-4-yl)phosphonate 
• 1584736-72-0 diphenyl ((4R,5R)-5-(4-methoxyphenyl)-4-phenyl-2-thioxo-1-tosylimidazolidin-4-yl)phosphonate 
• 1584736-73-1 diphenyl ((4R,5S)-4-phenyl-5-(thiophen-2-yl)-2-thioxo-1-tosylimidazolidin-4-yl)phosphonate 
• 1584736-78-6 C₂₉H₂₄NO₅PS 
• 1584736-75-3 diphenyl ((4R,5R)-3-acetyl-2-oxo-4,5-diphenyloxazolidin-4-yl)phosphonate 
• 1584736-76-4 diphenyl ((4R,5R)-2-oxo-4,5-diphenyloxazolidin-4-yl)phosphonate 
• 1584736-74-2 C₃₃H₂₈FN₂O₆PS 
• 1584736-65-1 diphenyl ((4R,5R)-4,5-diphenyl-2-thioxo-1-tosylimidazolidin-4-yl)phosphonate 
• 1584736-66-2 diphenyl ((4R,5R)-5-(4-fluorophenyl)-4-phenyl-2-thioxo-1-tosylimidazolidin-4-yl)phosphonate 
• 1584736-67-3 diphenyl ((4R,5R)-5-(4-chlorophenyl)-4-phenyl-2-thioxo-1-tosylimidazolidin-4-yl)phosphonate 
• 1584736-68-4 diphenyl ((4R,5R)-5-(2-chlorophenyl)-4-phenyl-2-thioxo-1-tosylimidazolidin-4-yl)phosphonate 

Relevant articles and documents

A novel theranostic activity-based probe targeting kallikrein 7 for the diagnosis and treatment of skin diseases

We applied a newin silicoapproach for using protease-substrate motifs to design a kallikrein 7 (KLK7)-specific phosphonate activity-based probe (ABP) to quantify the active KLK7in situ. Epidermal application of the ABP-inhibitor onSpink5?/?Klk5

Synthesis of phosphonodipeptide conjugates of ursolic acid and their homologs

To prepare novel derivatives of naturally bioactive 3β-hydroxy-urs-12- en-28-oic acid (ursolic acid) with unusual properties and broad spectrum of activities, a number of chemical reactions were conducted. First, a variety of a-aminophosphonates were prepared by a series of reactions involving the three-component Mannich type reaction as a key step. Second, an array of phosphonodipeptides and their homologs was synthesized through multistep reactions including condensation of phthalic anhydride with glycine or β-alanine, chlorination of N-blocked amino acids, coupling of acid chloride with α-aminophosphonates and sequential hydrazinolysis. Finally, new classes of phosphonodipeptide conjugates of ursolic acid and their homologs were obtained by condensation of 3β-acetoxy-urs-12-en-28-oyl chloride with phosphonodipeptides and their homologs.