84337-41-7

Basic information

• Product Name: 1-O-Hexadecyl-2-O-methyl-rac-glycerol
• Synonyms: 1-O-HEXADECYL-2-O-METHYL-RAC-GLYCEROL
• CAS NO: 84337-41-7
• Molecular Formula: C₂₀H₄₂O₃
• Molecular Weight: 330.55
• Mol File: 84337-41-7.mol
• Article Data: 6

Chemical Properties

• Boiling Point: 430.6±25.0 °C(Predicted)
• Appearance: /
• Density: 0.895±0.06 g/cm3(Predicted)
• PKA: 14.20±0.10(Predicted)
• CAS DataBase Reference: 1-O-Hexadecyl-2-O-methyl-rac-glycerol(CAS DataBase Reference)
• NIST Chemistry Reference: 1-O-Hexadecyl-2-O-methyl-rac-glycerol(84337-41-7)
• EPA Substance Registry System: 1-O-Hexadecyl-2-O-methyl-rac-glycerol(84337-41-7)

Safety Data

• Hazardous Substances Data: 84337-41-7(Hazardous Substances Data)

Upstream product

• 761-06-8 2-methylglycerol 
• 544-77-4 1-iodohexadecane 
• 89496-73-1 4-(n-hexadecyloxymethyl)-2,2-dimethyl-1,3-dioxolane 
• 118469-68-4 1-(hexadecyloxy)-3-((4-methoxyphenyl)diphenylmethoxy)-2-propanol 
• 6145-69-3 3-(hexadecyloxy)-1,2-propanediol 
• 112-82-3 hexadecanyl bromide 
• 138329-15-4 1-O-benzyl-2-O-methyl-3-O-hexadecyl-rac-glycerol 
• 6068-28-6 tosylate de n-hexadecyle 

Downstream Products

• 85405-05-6 1-O-hexadecyl-2-O-methylglycero-3-phosphocholine 
• 113521-09-8 Phosphoric acid 3-hexadecyloxy-2-methoxy-propyl ester 2-imidazol-1-yl-ethyl ester 
• 127164-64-1 Phosphoric acid 3-bromomethyl-phenyl ester 3-hexadecyloxy-2-methoxy-propyl ester 
• 140467-84-1 Phosphoric acid 4-bromomethyl-phenyl ester 3-hexadecyloxy-2-methoxy-propyl ester 
• 84337-29-1 C₂₇H₅₀NO₆P 

Relevant articles and documents

SALTS OF SUBSTITUTED ALLOPHANATES AND THEIR USE IN DRUGS

The invention relates to salts of substituted allophanates, to methods for producing them, to drugs containing said compounds and to the use of said compounds for producing drugs.

Analogues of Platelet Activating Factor. 6. Mono- and Bis-Aryl Phosphate Antagonists of Platelet Activating Factor

A series of aryl phosphoglyceride (3, 19-61) and bis-aryl phosphate (67-135) antagonists of platelet activating factor (PAF) were prepared.A group of four bifunctional phosphorus reagents (5a-c and 7) were developed that allowed the preparation of these aryl phosphates in which the position of aromatic substitution can be varied.These compounds were examined for their ability to inhibit PAF-induced platelet aggregation of rabbit platelets.Selected compounds were also evaluated for their ability to displace PAF from its receptor on rabbit platelets.These in vitro data were compared to similar data obtained for a number of known PAF antagonists.The compounds were evaluated in vivo, in both the mouse and rabbit, for their ability to prevent death induced by a lethal challenge of PAF.The relationships between the biological activity and the nature, lipophilicity, and position of substituents of the aromatic rings were studied.Compound 105 (CL 184005) has been selected to undergo further development as a potential therapeutic agent for the treatment of septic shock in man.

Synthesis and platelet-stimulating activities of structural analogues of the platelet-activating factor with heterocyclic head group

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