761-06-8

Basic information

• Product Name: 2-methoxypropane-1,3-diol
• Synonyms: 1,3-propanediol, 2-methoxy-; 2-Methoxypropane-1,3-diol
• CAS NO: 761-06-8
• Molecular Formula: C₄H₁₀O₃
• Molecular Weight: 106.1204
• Mol File: 761-06-8.mol
• Article Data: 6

Chemical Properties

• Boiling Point: 232°C at 760 mmHg
• Flash Point: 83.5°C
• Density: 1.101g/cm³
• Vapor Pressure: 0.0113mmHg at 25°C
• Refractive Index: 1.439
• CAS DataBase Reference: 2-methoxypropane-1,3-diol(CAS DataBase Reference)
• NIST Chemistry Reference: 2-methoxypropane-1,3-diol(761-06-8)
• EPA Substance Registry System: 2-methoxypropane-1,3-diol(761-06-8)

Safety Data

• Hazardous Substances Data: 761-06-8(Hazardous Substances Data)

Upstream product

• 56-81-5 glycerol 
• 99586-36-4 5-methoxy-1,3-dioxane 
• 7647-01-0 hydrogenchloride 
• 104216-84-4 5-methoxy-2-phenyl-1,3-dioxane 
• 97924-47-5 2-methoxy-1,3-bis-trityloxy-propane 
• 10035-10-6 hydrogen bromide 
• 64-19-7 acetic acid 
• 71-43-2 benzene 
• 67-56-1 methanol 
• 556-52-5 oxiranyl-methanol 
• 77-78-1 dimethyl sulfate 
• 103797-30-4 5-methoxy-2-(4-nitro-phenyl)-[1,3]dioxane 

Downstream Products

• 106382-18-7 2-O-Methyl-1,3-di-O-p-phenylazobenzoyl-glycerin 
• 73757-48-9 5-Methoxy-2-phenoxy-[1,3,2]dioxaphosphinane 2-oxide 
• 73757-47-8 5-Methoxy-2-phenoxy-[1,3,2]dioxaphosphinane 2-oxide 
• 84337-41-7 3-(hexadecyloxy)-2-methoxy-1-propanol 
• 84337-43-9 2-methoxy-3-octadecyloxy-1-propanol 
• 103797-30-4 5-methoxy-2-(4-nitro-phenyl)-[1,3]dioxane 
• 20637-49-4 1,2,3-trimethoxy glycerol ether 
• 18679-04-4 rac.-1-Stearoyl-glycerin-methylaether-2 
• 68755-18-0 5-methoxytrimethylenephosphoric acid phenyl ester 
• 1073630-78-0 (+/-)-2-methoxy-3-{[5-(4-methoxyphenyl)-6-phenylfuro[2,3-d]pyrimidin-4-yl]oxy}propan-1-ol 
• 128420-67-7 1,3-O-diphenyloxycarbonyl-2-O-methylglycerol 
• 126953-08-0 (S)-1-O-acetyl-2-O-methylglycerol 
• 128188-17-0 (R)-1-O-acetyl-2-O-methylglycerol 

Relevant articles and documents

Regioselective Ring-Opening of Glycidol to Monoalkyl Glyceryl Ethers Promoted by an [OSSO]-FeIII Triflate Complex

A FeIII-triflate complex, bearing a bis-thioether-di-phenolate [OSSO]-type ligand, was discovered to promote the ring-opening of glycidol with alcohols under mild reaction conditions (0.05 mol % catalyst and 80 °C). The reaction proceeded with high activity (initial turnover frequency of 1680 h?1 for EtOH) and selectivity (>95 %) toward the formation of twelve monoalkyl glyceryl ethers (MAGEs) in a regioselective fashion (84–96 % yield of the non-symmetric regioisomer). This synthetic approach allows the conversion of a glycerol-derived platform molecule (i.e., glycidol) to high-value-added products by using an Earth-crust abundant metal-based catalyst.

Synthesis of Monoalkyl Glyceryl Ethers by Ring Opening of Glycidol with Alcohols in the Presence of Lewis Acids

The present work deals with the production of monoalkyl glyceryl ethers (MAGEs) through a new reaction pathway based on the reaction of glycidol and alcohols catalyzed by Lewis acid-based catalysts. Glycidol is quantitatively converted with high selectivity (99 %) into MAGEs under very mild reaction conditions (80 °C and 0.01 mol % catalyst loading) in only 1 h using Al(OTf)3 or Bi(OTf)3 as catalyst. The proposed method enhances the choice of possible green synthetic approaches for the production of value-added products such as MAGEs.

Graphene oxide as an acid catalyst for the room temperature ring opening of epoxides

The minute amount of hydrogen sulfate groups introduced into the graphene oxide (GO) obtained by Hummers oxidation of graphite renders this material as a highly efficient, recyclable acid catalyst for the ring opening of epoxides with methanol and other primary alcohols as nucleophile and solvent.