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84416-82-0

5'-O-(4,4'-Dimethoxytrityl)-N6-Benzoyl-2'-Deoxyadenosine-3'-(Methyl-N,N-Diisopropyl)Phosphoramidite is a complex organic compound widely used in the synthesis of oligonucleotides, particularly in the field of DNA and RNA chemistry. This chemical serves as a protected building block for the construction of nucleic acid sequences, with its structure designed to facilitate the addition of adenosine units to growing oligonucleotide chains. The 5'-O-(4,4'-Dimethoxytrityl) group provides a photosensitive protecting group that can be removed using UV light, while the N6-Benzoyl group protects the exocyclic amine of the adenine base. The 2'-Deoxyribose sugar is devoid of an oxygen atom at the 2' position, which is characteristic of DNA. Lastly, the 3'-(Methyl-N,N-Diisopropyl)Phosphoramidite moiety includes a phosphoramidite group for coupling to the next nucleotide and a methyl group that, along with the diisopropyl groups, serves as a protecting group for the 3'-hydroxyl group, preventing unwanted side reactions during synthesis. 5'-O-(4,4'-DIMETHOXYTRITYL)-N6-BENZOYL-2'-DEOXYADENOSINE-3'-(METHYL-N,N-DIISOPROPYL)PHOSPHORAMIDITE is crucial for the controlled and efficient assembly of DNA and RNA molecules in various applications, including genetic research, drug discovery, and the development of diagnostic tools.

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  • 84416-82-0 Structure

  • Basic information

    1. Product Name: 5'-O-(4,4'-DIMETHOXYTRITYL)-N6-BENZOYL-2'-DEOXYADENOSINE-3'-(METHYL-N,N-DIISOPROPYL)PHOSPHORAMIDITE
    2. Synonyms: 5'-O-(4,4'-DIMETHOXYTRITYL)-N6-BENZOYL-2'-DEOXYADENOSINE-3'-(METHYL-N,N-DIISOPROPYL)PHOSPHORAMIDITE;N6-BENZOYL-5''-O-(4,4''-DIMETHOXYTRITYL) 2''-DEOXYADENOSINE 3''-METHYL, N,-DIISOPROPYL) PHOSPHORAMIDITE);dimethoxytrityl-deoxyadenosine phosphoramidite;N6-Benzoyl-2'-deoxy-5'-O-DMT-adenosine 3'-Me phosphonamidite
    3. CAS NO:84416-82-0
    4. Molecular Formula: C45H51N6O7P
    5. Molecular Weight: 818.9
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 84416-82-0.mol

  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: /
    5. Density: N/A
    6. Refractive Index: N/A
    7. Storage Temp.: Store at -20°C
    8. Solubility: N/A
    9. CAS DataBase Reference: 5'-O-(4,4'-DIMETHOXYTRITYL)-N6-BENZOYL-2'-DEOXYADENOSINE-3'-(METHYL-N,N-DIISOPROPYL)PHOSPHORAMIDITE(CAS DataBase Reference)
    10. NIST Chemistry Reference: 5'-O-(4,4'-DIMETHOXYTRITYL)-N6-BENZOYL-2'-DEOXYADENOSINE-3'-(METHYL-N,N-DIISOPROPYL)PHOSPHORAMIDITE(84416-82-0)
    11. EPA Substance Registry System: 5'-O-(4,4'-DIMETHOXYTRITYL)-N6-BENZOYL-2'-DEOXYADENOSINE-3'-(METHYL-N,N-DIISOPROPYL)PHOSPHORAMIDITE(84416-82-0)

  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 84416-82-0(Hazardous Substances Data)

84416-82-0 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 84416-82-0 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 8,4,4,1 and 6 respectively; the second part has 2 digits, 8 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 84416-82:
(7*8)+(6*4)+(5*4)+(4*1)+(3*6)+(2*8)+(1*2)=140
140 % 10 = 0
So 84416-82-0 is a valid CAS Registry Number.

84416-82-0SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 18, 2017

Revision Date: Aug 18, 2017

1.Identification

1.1 GHS Product identifier

Product name 5'-O-dimethoxytrityl-6-N-benzoyldeoxyadenosine 3'-(N,N-diisopropyl-O-methyl)phosphoramidite

1.2 Other means of identification

Product number -
Other names -

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

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More Details:84416-82-0 SDS

84416-82-0Downstream Products

84416-82-0Relevant articles and documents

Rapid and efficient syntheses of phosphorylated dinucleotides

Ferris,Peyser

, p. 1087 - 1111 (2007/10/02)

Nine or ten-step solution phase syntheses of the dimers dpApA, dApAp, dpTpT and dTpTp in 0.1-0.5 g amounts, in overall yields of 49%, 45%, 32%, and 20% respectively, are described. The synthetic intermediates were characterized by 1H and 3

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