84456-99-5Relevant articles and documents
Pd-Catalyzed Csp2-H Functionalization of Heteroarenes via Isocyanide Insertion: Concise Synthesis of Di-(Hetero)Aryl Ketones and Di-(Hetero)Aryl Alkylamines
Sharma, Upendra K.,Sharma, Nandini,Xu, Jun,Song, Gonghua,Van Der Eycken, Erik V.
supporting information, p. 4908 - 4912 (2015/03/30)
We report herein an efficient Pd-catalyzed direct C-H bond functionalization of heteroarenes via an isocyanide insertion strategy for the synthesis of di-(hetero)aryl ketones and di-(hetero)aryl alkylamines. The methodology involves a three component reaction between an azole, a haloarene and an isocyanide resulting in the formation of an imine, which in turn is either hydrolyzed or reduced to get the desired product.
A facile and expeditious one-pot synthesis of α-Keto-1,3,4- oxadiazoles
Kumar, Dalip,Pilania, Meenakshi,Arun,Mishra, Bhupendra
, p. 1137 - 1141 (2014/05/20)
An efficient and high-yielding protocol for the preparation of α-keto-1,3,4-oxadiazoles has been developed. Formation of α-keto-1,3,4-oxadiazoles involves the 2-iodoxybenzoic acid/ tetraethylammonium bromide mediated oxidative cyclization of hydrazide-hyd
TETRAZOLES IN THE SYNTHESES OF 1,3,4-OXADIAZOLES
Koldobskii, G. I.,Ivanova, S. E.
, p. 1512 - 1517 (2007/10/03)
Various variants of cleavage of tetrazoles to form 1,3,4-oxadiazoles are examined.The mechanisms and synthetic potentialities of these reactions are discussed.
