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3-(methoxycarbonyl)cyclopentanecarboxylic acid is a carboxylic acid derivative with the molecular formula C9H14O4. It features a cyclopentane ring with a methoxycarbonyl group attached at position 3, making it a white, crystalline solid that is insoluble in water but soluble in organic solvents. This chemical compound serves as a valuable building block in organic synthesis and pharmaceutical research.

84545-00-6

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84545-00-6 Usage

Uses

Used in Organic Synthesis:
3-(methoxycarbonyl)cyclopentanecarboxylic acid is used as a building block for the synthesis of various organic compounds. Its unique structure and reactivity make it a versatile component in the creation of complex molecules.
Used in Pharmaceutical Research:
In the pharmaceutical industry, 3-(methoxycarbonyl)cyclopentanecarboxylic acid is used as a key intermediate in the development of new drugs. Its chemical properties allow for the formation of diverse pharmaceutical products with potential therapeutic applications.
Used in Agrochemical Products:
3-(methoxycarbonyl)cyclopentanecarboxylic acid is also utilized in the agrochemical sector for the synthesis of various agrochemicals. Its ability to form a wide range of compounds makes it a valuable asset in the development of products for agricultural use.

Check Digit Verification of cas no

The CAS Registry Mumber 84545-00-6 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 8,4,5,4 and 5 respectively; the second part has 2 digits, 0 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 84545-00:
(7*8)+(6*4)+(5*5)+(4*4)+(3*5)+(2*0)+(1*0)=136
136 % 10 = 6
So 84545-00-6 is a valid CAS Registry Number.

84545-00-6SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 19, 2017

Revision Date: Aug 19, 2017

1.Identification

1.1 GHS Product identifier

Product name 3-methoxycarbonylcyclopentane-1-carboxylic acid

1.2 Other means of identification

Product number -
Other names -

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:84545-00-6 SDS

84545-00-6Relevant articles and documents

Pharmacophore-Based Design of Phenyl-[hydroxycyclohexyl] Cycloalkyl-Carboxamide Mitofusin Activators with Improved Neuronal Activity

Bernstein, Peter R.,Dang, Xiawei,Devanathan, Sriram,Dorn, Gerald W.,Franco, Antonietta,Fu, Lijun,Walters, Daniel,Williams, Sidney B.

, p. 12506 - 12524 (2021/09/11)

Mitochondrial fragmentation from defective fusion or unopposed fission contributes to many neurodegenerative diseases. Small molecule mitofusin activators reverse mitochondrial fragmentation in vitro, promising a novel therapeutic approach. The first-in-c

HETEROARYLDIHYDROPYRIMIDINE DERIVATIVES AND METHODS OF TREATING HEPATITIS B INFECTIONS

-

Page/Page column 35; 36, (2019/01/17)

Provided herein are compounds useful for the treatment of HBV infection in a subject in need thereof, pharmaceutical compositions thereof, and methods of inhibiting, suppressing, or preventing HBV infection in the subject.

Conformational Restriction and Enantioseparation Increase Potency and Selectivity of Cyanoguanidine-Type Histamine H4 Receptor Agonists

Geyer, Roland,Nordemann, Uwe,Strasser, Andrea,Wittmann, Hans-Joachim,Buschauer, Armin

supporting information, p. 3452 - 3470 (2016/05/19)

2-Cyano-1-[4-(1H-imidazol-4-yl)butyl]-3-[2-(phenylsulfanyl)ethyl]guanidine (UR-PI376, 1) is a potent and selective agonist of the human histamine H4 receptor (hH4R). To gain information on the active conformation, we synthesized analogues of 1 with a cyclopentane-1,3-diyl linker. Affinities and functional activities were determined at recombinant hHxR (x: 1-4) subtypes on Sf9 cell membranes (radioligand binding, [35S]GTPγS, or GTPase assays) and in part in luciferase assays on human or mouse H4R (HEK-293 cells). The most potent H4R agonists among 14 racemates were separated by chiral HPLC, yielding eight enantiomerically pure compounds. Configurations were assigned based on X-ray structures of intermediates and a stereocontrolled synthetic pathway. (+)-2-Cyano-1-{[trans-(1S,3S)-3-(1H-imidazol-4-yl)cyclopentyl]methyl}-3-[2-(phenylsulfanyl)ethyl]guanidine ((1S,3S)-UR-RG98, 39a) was the most potent H4R agonist in this series (EC50 11 nM; H4R vs H3R, >100-fold selectivity; H1R, H2R, negligible activities), whereas the optical antipode proved to be an H4R antagonist ([35S]GTPγS assay). MD simulations confirmed differential stabilization of the active and inactive H4R state by the enantiomers.

CYCLOALKYL-LINKED DIHETEROCYCLE DERIVATIVES

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Page/Page column 147; 148, (2015/11/24)

The present invention relates to compounds of formula (I) or pharmaceutically acceptable salts thereof, wherein A, L, D, R1-R15, w, x, y, and z are defined herein. The novel cycloalkyl-linked diheterocycle derivatives that are useful in the treatment of abnormal cell growth, such as cancer, in mammals. The present invention also relates to pharmaceutical compositions containing the compounds and to methods of using the compounds and compositions in the treatment of abnormal cell growth in mammals.

Enantioselective synthesis of (+) and (-)-cis-3-aminocyclopentanecarboxylic acids by enzymatic asymmetrization

Chenevert,Martin

, p. 199 - 200 (2007/10/02)

Both enantiomers of cis-3-aminocyclopentanecarboxylic acid (GABA analogs, inhibitory neurotransmitter) have been prepared via enzymatic asymmetrization of cis -1,3-cyclopentanedicarboxylic acid.

Reaction Pathways of 3-(3'-Methylenecyclobutyl)propyl and 2-(3'-Methylenecyclobutyl)ethyl Radicals

Pigou, Paul E.

, p. 4943 - 4950 (2007/10/02)

Molecular mechanics (MM2) calculations were used to predict the efficacy and regiochemical outcome of radical cyclizations involving the title radicals and others with further substitution at C1 on the ring.The MM2 results were generally ratifi

Enzymes in organic synthesis. 33. Stereoselective pig liver esterase-catalyzed hydrolyses of meso cyclopentyl-, tetrahydrofuranyl-, and tetrahydrothiophenyl-1,3-diesters

Jones, J. Bryan,Hinks, R. Scott,Hultin, Philip G.

, p. 452 - 456 (2007/10/02)

Preparative-scale pig liver esterase-catalyzed hydrolyses of five-membered ring meso-1,3-diesters are enantiotopically selective.While pro-S enantiotopic selectivity is exhibited in each case, the absolute configuration sense of the hydrolysis in the cyclopentyl series is opposite to that of both the tetrahydrofuranyl and tetrahydrothiophenyl diesters.The enantiomeric excess levels induced are in the 34-46percent range.

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