84547-62-6Relevant academic research and scientific papers
SUBSTITUTED GUANIDINE DERIVATIVE
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Paragraph 1632; 1633, (2018/06/23)
The present invention provides a compound of general formula (I) (wherein, R1, X, p and q are as described in the present description and claims), or a pharmacologically acceptable salt thereof, and a pharmaceutical composition containing that compound.
HETEROCYCLIC COMPOUNDS FOR THE INHIBITION OF PASK
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Paragraph 0175, (2014/05/24)
Disclosed herein are new heterocyclic compounds and compositions and their application as pharmaceuticals for the treatment of disease. Methods of inhibiting PAS Kinase (PASK) activity in a human or animal subject are also provided for the treatment of diseases such as diabetes mellitus.
BICYCLIC COMPOUNDS WHICH INHIBIT BETA-SECRETASE ACTIVITY AND METHODS OF USE THEREOF
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Page/Page column 60-61, (2010/10/20)
The present invention provides bicyclic beta-secretase inhibitors and methods for their use, including methods of treating of Alzheimer’s disease.
Synthesis and antibacterial activity of novel 4-pyrrolidinylthio carbapenems. Part IV. 2-Alkyl substituents containing cationic heteroaromatics linked via a C-C bond
Azami, Hidenori,Barrett, David,Tanaka, Akira,Sasaki, Hiroshi,Matsuda, Keiji,Sakurai, Minoru,Terasawa, Takeshi,Shirai, Fumiyuki,Chiba, Toshiyuki,Matsumoto, Yoshimi,Tawara, Shuichi
, p. 961 - 982 (2007/10/03)
The synthesis and biological activity of a novel series of 2-alkyl-4-pyrrolidinylthio-β-methylcarbapenems containing a variety of cationic heteroaromatic substituents linked via a C-C bond is described. As a result of these studies, we selected FR21818 (1
Cephalosporin derivatives
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, (2008/06/13)
Novel cephalosporin derivatives and physiologically acceptable salts thereof which are useful as antibacterial agents against gram-negative and gram-positive bacteria, and a process for preparing these compounds are disclosed.
Synthesis of Macrobicyclic Ligands containing Pyrazole Subunits: the N,N'-Bipyrazolyl Cryptand
Juanes, Olga,Mendoza, Javier de,Rodriguez-Ubis, Juan-Carlos
, p. 1765 - 1766 (2007/10/02)
The pyrazolyl cryptands (1) and (2) have been obtained in one-step, non high-dilution macrobicyclization reaction, from a 1,1'-bipyrazole derivative; similarly, tripodal ligands (7)-(9) with pyrazole structures are described.
