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"Z-Trp-Lys(Mtr)-Gly-OBut" is a peptide compound consisting of four amino acids: Z-protected tryptophan (Trp), methionine-containing tryptophan (Lys(Mtr)), glycine (Gly), and tert-butyl-protected (OBut) group. This sequence is a specific arrangement of amino acids, which are the building blocks of proteins. The "Z" group is a protecting group used in peptide synthesis to prevent unwanted side reactions, while the "Mtr" group is a modification of the lysine amino acid, often used to introduce specific properties or functions to the peptide. The "OBut" group is another protecting group, which is used to protect the peptide from degradation or unwanted reactions during synthesis. This particular peptide sequence is of interest in the field of biochemistry and may have applications in drug development, as modified peptides can be used to target specific biological processes or receptors.

84552-41-0

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84552-41-0 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 84552-41-0 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 8,4,5,5 and 2 respectively; the second part has 2 digits, 4 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 84552-41:
(7*8)+(6*4)+(5*5)+(4*5)+(3*2)+(2*4)+(1*1)=140
140 % 10 = 0
So 84552-41-0 is a valid CAS Registry Number.

84552-41-0Relevant academic research and scientific papers

4-Methoxy-2,3,6-trimethylbenzenesulfonyl (Mtr): a New Amino and Imidazole Protecting Group in Peptide Synthesis

Wakimasu, Mitsuhiro,Kitada, Chieko,Fujino, Masahiko

, p. 2766 - 2779 (2007/10/02)

The 4-methoxy-2,3,6-trimethylbenzenesulfonyl (Mtr) group was introduced as a protecting group for the amino function, especially the ε-amino function of lysine, and the imidazole ring of histidine.The Nε-Mtr group was removable by dilute methanesulfonic acid-containing trifluoroacetic acid-thioanisole, but was stable to trifluoroacetic acid or catalytic hydrogenation.The Nim-Mtr group was removable by trifluoroacetic acid-dimethylsulfide or 1-hydroxybenzotriazole, but was more stable than the Nim-Tos or the Nim-Mbs group with triethylamine.To examine the usefulness of the Mtr group as a protecting group for use in peptide synthesis, mastoparan X and chicken gastrin releasing peptide (c-GRP) were synthesized, and this group was found to be very convenient for general solution synthesis.In particular, the introduction of Lys(Mtr) made possible a new strategy in peptide synthesis.Keywords-4-methoxy-2,3,6-trimethylbenzenesulfonyl (Mtr); Nε-4-methoxy-2,3,6-trimethylbenzenesulfonyllysine; Nim-4-methoxy-2,3,6-trimethylbenzenesulfonylhistidine; methanesulfonic acid-trifluoroacetic acid-thioanisole deprotection; trifluoroacetic acid-dimethylsulfide deprotection; mastoparan X; chicken gastrin releasing peptide

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