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Z-Lys(Mtr)-OH is a synthetic peptide derivative, where "Z" stands for the benzyloxycarbonyl (Cbz) protecting group, "Lys" represents the amino acid lysine, "Mtr" denotes the 4-methoxy-2,3,6-trimethylbenzenesulfonyl (Mtr) group, and "OH" indicates the presence of a hydroxyl group. Z-Lys(Mtr)-OH is commonly used in peptide synthesis as a protected amino acid building block. The Mtr group serves as a side-chain protecting group for lysine, which is crucial for preventing unwanted side reactions during peptide assembly. The hydroxyl group at the end of the molecule allows for further elongation of the peptide chain. Z-Lys(Mtr)-OH is a valuable component in the synthesis of complex peptides and proteins, particularly in research and pharmaceutical applications where controlled peptide assembly is essential.

83031-07-6

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83031-07-6 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 83031-07-6 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 8,3,0,3 and 1 respectively; the second part has 2 digits, 0 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 83031-07:
(7*8)+(6*3)+(5*0)+(4*3)+(3*1)+(2*0)+(1*7)=96
96 % 10 = 6
So 83031-07-6 is a valid CAS Registry Number.

83031-07-6Relevant academic research and scientific papers

4-Methoxy-2,3,6-trimethylbenzenesulfonyl (Mtr): a New Amino and Imidazole Protecting Group in Peptide Synthesis

Wakimasu, Mitsuhiro,Kitada, Chieko,Fujino, Masahiko

, p. 2766 - 2779 (2007/10/02)

The 4-methoxy-2,3,6-trimethylbenzenesulfonyl (Mtr) group was introduced as a protecting group for the amino function, especially the ε-amino function of lysine, and the imidazole ring of histidine.The Nε-Mtr group was removable by dilute methanesulfonic acid-containing trifluoroacetic acid-thioanisole, but was stable to trifluoroacetic acid or catalytic hydrogenation.The Nim-Mtr group was removable by trifluoroacetic acid-dimethylsulfide or 1-hydroxybenzotriazole, but was more stable than the Nim-Tos or the Nim-Mbs group with triethylamine.To examine the usefulness of the Mtr group as a protecting group for use in peptide synthesis, mastoparan X and chicken gastrin releasing peptide (c-GRP) were synthesized, and this group was found to be very convenient for general solution synthesis.In particular, the introduction of Lys(Mtr) made possible a new strategy in peptide synthesis.Keywords-4-methoxy-2,3,6-trimethylbenzenesulfonyl (Mtr); Nε-4-methoxy-2,3,6-trimethylbenzenesulfonyllysine; Nim-4-methoxy-2,3,6-trimethylbenzenesulfonylhistidine; methanesulfonic acid-trifluoroacetic acid-thioanisole deprotection; trifluoroacetic acid-dimethylsulfide deprotection; mastoparan X; chicken gastrin releasing peptide

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