84713-51-9

Upstream product

• 64-17-5 ethanol 
• 116432-33-8 (+)-(2R,3S)-3,4-dimethyl-2,5-diphenyl-nitrobenzo<4,3-g>1,6-dioxa-4-aza-5-phospha (5-PV) spiro <4.4>nonane 
• 772-33-8 Koshlands reagent I 
• 1638-86-4 diethyl phenylphosphonite 
• 87214-07-1 (4S,5R)-3,4-Dimethyl-2,5-diphenyl-[1,3,2]oxazaphospholidine 

Downstream Products

• 84713-49-5 2-phenyl-nitrobenz<3,4-d> 1,2-oxaphospholane-2-oxide 

Relevant academic research and scientific papers

Aminolysis of Activated Esters Formed by Reaction of Carboxylate Salts with Strained Phosphonates and Phosphinates

Nucleophilic attack of a carboxylate salt on a five membered phosphonic or phosphinic ester followed by an intramolecular acyl transfer reaction gives a substituted aryl ester.Due to the intramolecular base catalysis of a neighbouring P=O group the bimolecular aminolysis of this ester is a fast process.

CHIRAL BICYCLIC SPIROPHOSPHORANES IN AN ARBUZOV-TYPE REACTION

The reaction of 2-hydroxy-5-nitro-benzyl halides with three chiral five-or six-membered oxaphosphacycloalkanes has been studied.In each case, a 31P NMR analysis shows the formation of resonance signals in the phosphorane region but these phosphoranes are usually unstable.However both enantiomers of the 2-phenyl-1,3,2-oxazaphospholidine give chiral bicyclic spirophosphoranes which have been characterized by 31P and 1H NMR and high resolution mass spectroscopies.