84725-18-8

Upstream product

• 22966-19-4 trans-4'-methoxychalcone 
• 105-45-3 acetoacetic acid methyl ester 
• 959-23-9 4'-methoxychalcone 
• 100-06-1 1-(4-methoxyphenyl)ethanone 
• 100-52-7 benzaldehyde 

Downstream Products

• 25960-26-3 3-(p-methoxyphenyl)-5-phenylcyclohex-2-en-1-one 
• 84725-19-9 6-(p-methoxyphenyl)-3-oxo-4-phenyl-3,3a,4,5-tetrahydro-2H-benzopyrazole 
• 93938-59-1 1-(p-methoxyphenyl)-5-phenylcyclohex-6-ene-4-carboxylic acid 
• 93938-60-4 1-(p-methoxyphenyl)-5-phenylcyclohex-1-ene-4-carboxylic acid 
• 93938-62-6 4-(4-Methoxy-phenyl)-6-phenyl-cyclohex-3-enecarboxylic acid methyl ester 
• 93938-57-9 4-(4-Methoxy-phenyl)-2-phenyl-cyclohex-3-enecarboxylic acid methyl ester 
• 93938-54-6 4-carbomethoxy-1-(p-methoxyphenyl)-5-phenylcyclohex-6-en-3-ethylenethioketal 
• 93938-61-5 4-carbomethoxy-1-(p-methoxyphenyl)-5-phenylcyclohex-1-en-3-ethylenethioketal 
• 84725-20-2 6-(p-methoxyphenyl)-3-oxo-2,4-diphenyl-3,3a,4,5-tetrahydrobenzopyrazole 
• 25960-27-4 3-(p-hydroxyphenyl)-5-phenylcyclohex-2-en-1-one 
• 148215-40-1 3-(p-methoxyphenyl)-5-phenylcyclohex-2-en-1-ol 
• 345937-18-0 1-acetoxy-3-(p-methoxyphenyl)-5-phenylcyclohex-2-ene 
• 84750-33-4 3--5-phenylcyclohex-2-en-1-one 
• 84725-21-3 3-acetoxy-2-acetyl-6-(p-methoxyphenyl)-4-phenyl-4,5-dihydrobenzopyrazole 

Relevant academic research and scientific papers

Studies in Antifertility Agents: Part XL - Synthesis of 1--3,5-diphenylbenzene and 1,5-Diphenylcyclohexene Derivatives

4-Carbomethoxy-1-(p-methoxyphenyl)-5-phenylcyclohex-1-en-3-one (1) and its 6-ethyl derivative (2) on acid hydrolysis undergo decarbomethoxylation to give 3 and 4 respectively.Addition of PhMgBr onto 3 followed by demethylation of the resulting carbinol (5

Studies in Antifertility Agents: Part XXXVII--Synthesis of 3-Aryl-5-phenylcyclohex-2-en-1-ones and 4,6-Diphenyl-2,3-disubstituted-benzopyrazoles

Condensation of methyl acetoacetate with 4'-methoxychalkone (1) gives 6-carbomethoxy-3-(p-methoxyphenyl)-5-phenylcyclohex-2-en-1-one (2) which on reaction with hydrazine hydrate and phenylhydrazine yields 3-oxo-4,6-diphenyl-3,3a,4,5-tetrahydrobenzopyrazoles (3 and 4).Treatment of 2 with aq.H2SO4-AcOH results in decarboxylation to yield the corresponding cyclohexenone (6) which on KBH4 reduction gives cyclohexen-1-ol (7).Acetylation of 3 and 7 gives the respective acetates (5 and 7).Demethylation of 6 affords the corresponding 3-(p-hydroxyphenyl) derivative (9) which on treatment with 1-(β-chloroethyl)pyrrolidine furnishes the desired compound, 3--5-phenylcyclohex-2-en-1-one (10).None of the compounds prevents pregnancy in female albino rats at 10 mg/kg dose.