84741-86-6

Basic information

• Product Name: QUINOLINE-3-CARBONYL CHLORIDE
• Synonyms: QUINOLINE-3-CARBONYL CHLORIDE;3-Quinolinecarbonyl chloride
• CAS NO: 84741-86-6
• Molecular Formula: C₁₀H₆ClNO
• Molecular Weight: 191.62
• Mol File: 84741-86-6.mol
• Article Data: 44

Chemical Properties

• Appearance: /
• CAS DataBase Reference: QUINOLINE-3-CARBONYL CHLORIDE(CAS DataBase Reference)
• NIST Chemistry Reference: QUINOLINE-3-CARBONYL CHLORIDE(84741-86-6)
• EPA Substance Registry System: QUINOLINE-3-CARBONYL CHLORIDE(84741-86-6)

Safety Data

• Hazardous Substances Data: 84741-86-6(Hazardous Substances Data)

Upstream product

• 6480-68-8 quinoline-3-carboxylic acid 
• 79-37-8 oxalyl dichloride 
• 5332-24-1 3-bromoquinoline 
• 201230-82-2 carbon monoxide 
• 141-75-3 butyryl chloride 

Downstream Products

• 37045-14-0 phenyl(quinolin-3-yl)methanone 
• 685141-86-0 3-phenyl-2(RS)-{2-[(quinoline-3-carbonyl)-amino]-benzoylamino}-propionic acid ethyl ester 
• 113058-27-8 phenyl(4-phenylquinolin-3-yl)methanone 
• 1042352-94-2 N-[5-(cyclohexylmethyl)-4-(2,5-dimethoxy-4-methylphenyl)pyrimidin-2-yl]quinoline-3-carboxamide 
• 1221290-87-4 N-{2-[4-(3-fluorophenyl)piperazin-1-yl]ethyl}-3-quinoline carboxamide 
• 1218777-65-1 N-[2-(4-phenyl-1,2,3,6-tetrahydropyridin-1-yl)ethyl]-3-quinoline carboxamide 
• 1218777-62-8 N-[2-(4-phenylpiperazin-1-yl)ethyl]-3-quinolinecarboxamide 
• 1221290-94-3 N-{2-[4-(4-methylphenyl)piperazin-1-yl]ethyl}-3-quinoline carboxamide 
• 1221290-92-1 N-{2-[4-(2-methylphenyl)piperazin-1-yl]ethyl}-3-quinoline carboxamide 
• 1221290-91-0 N-{2-[4-(4-chlorophenyl)piperazin-1-yl]ethyl}-3-quinoline carboxamide 
• 1221290-97-6 N-{2-[4-(3-methoxylphenyl)piperazin-1-yl]ethyl}-3-quinoline carboxamide 
• 1221290-89-6 N-{2-[4-(2-chlorophenyl)piperazin-1-yl]ethyl}-3-quinoline carboxamide 
• 1221290-96-5 N-{2-[4-(2-methoxylphenyl)piperazin-1-yl]ethyl}-3-quinoline carboxamide 
• 1221290-93-2 N-{2-[4-(3-methylphenyl)piperazin-1-yl]ethyl}-3-quinoline carboxamide 

Relevant articles and documents

Crystal structure, Hirshfeld surface analysis and DFT studies of N-(4-acetylphenyl)quinoline-3-carboxamide

Crystalline organic compound, N-(4-acetylphenyl)quinoline-3-carboxamide (4) was readily prepared using our previously reported experimental procedure by the reaction of quinoline-3-carboxylic acid (1) with thionyl chloride to generate the acid chloride in

Palladium-Catalyzed Chlorocarbonylation of Aryl (Pseudo)Halides Through In Situ Generation of Carbon Monoxide

An efficient palladium-catalyzed chlorocarbonylation of aryl (pseudo)halides that gives access to a wide range of carboxylic acid derivatives has been developed. The use of butyryl chloride as a combined CO and Cl source eludes the need for toxic, gaseous carbon monoxide, thus facilitating the synthesis of high-value products from readily available aryl (pseudo)halides. The combination of palladium(0), Xantphos, and an amine base is essential to promote this broadly applicable catalytic reaction. Overall, this reaction provides access to a great variety of carbonyl-containing products through in situ transformation of the generated aroyl chloride. Combined experimental and computational studies support a reaction mechanism involving in situ generation of CO.

Ultrasound-assisted synthesis of novel chalcone, heterochalcone and bis-chalcone derivatives and the evaluation of their antioxidant properties and as acetylcholinesterase inhibitors

The chalcone and bis-chalcone derivatives have been synthesized under sonication conditions via Claisen-Schmidt condensation with KOH in ethanol at room temperature (20–89%). The structures were established on the basis of NMR, IR, Single-crystal XRD, and