847448-30-0

Upstream product

• 34036-07-2 3,4 difluorobenzaldehyde 
• 557-20-0 diethylzinc 

Downstream Products

• 847448-41-3 {[(R)-1-(3,4-Difluoro-phenyl)-propyl]-formyl-amino}-acetic acid methyl ester 
• 847448-38-8 [(R)-1-(3,4-Difluoro-phenyl)-propylamino]-acetic acid methyl ester 
• 847448-32-2 (R)-1-(3,4-difluorophenyl)propylamine 
• 847448-31-1 4-((R)-1-Azido-propyl)-1,2-difluoro-benzene 

Relevant academic research and scientific papers

Ar-BINMOLs with axial and sp3 central chirality - Characterization, chiroptical properties, and application in asymmetric catalysis

2′-Hydroxy-1,1′-binaphthalene-2-(arylmethanol) (Ar-BINMOLs), a family of new 1,1′-binaphthalene-2,2′-diol derivatives, prepared by a [1,2]-Wittig rearrangement, are introduced as new chiral molecules for the study of the modes of supramolecular aggregatio

2-Mercaptoimidazoles, a new class of potent CCR2 antagonists

We describe the synthesis and SAR of a new class of CCR2 antagonists based on a 2-mercaptoimidazole scaffold. The initial lead 1a was optimized to the 3,4-disubstituted analogues 1p-(S) and 1q-(S), which have IC50 values in the MCP-1 induced Ca