848949-86-0

Usage

Uses

Used in Pharmaceutical Industry:
Leucine, N-(diphenylmethylene)-4-fluoro-, ethyl ester is used as a building block for drug molecules in the pharmaceutical industry. Its ability to form stable complexes with various functional groups makes it a valuable component in drug design and development.
Used in Organic Synthesis:
Leucine, N-(diphenylmethylene)-4-fluoro-, ethyl ester is used as a reagent in organic synthesis due to its ability to form stable complexes with various functional groups, facilitating the synthesis of complex organic compounds.
Used in Drug Design and Development:
The unique properties of Leucine, N-(diphenylmethylene)-4-fluoro-, ethyl ester, such as increased lipophilicity and hydrophobicity, make it a valuable component in drug design and development. Its fluorinated structure can enhance the pharmacokinetic and pharmacodynamic properties of drug molecules, improving their efficacy and safety.
Used in Research Settings:
Leucine, N-(diphenylmethylene)-4-fluoro-, ethyl ester is used in research settings to study its effects on biological systems and explore potential therapeutic applications. Its unique properties and interactions with various functional groups make it a promising candidate for the development of new drugs and therapeutic agents.

Upstream product

• 69555-14-2 ethyl N-diphenylmethylene glycine 
• 145349-17-3 (2-fluoro-2-methylpropyl) trifluoromethanesulfonate 

Downstream Products

• 848949-87-1 2-benzoylamino-4-fluoro-4-methyl-pentanoic acid 
• 848949-85-9 ethyl (2S)-2-amino-4-fluoro-4-methylpentanoate sulfate salt 
• 848949-91-7 (S)-2-Benzoylamino-4-fluoro-4-methyl-pentanoic acid ethyl ester 
• 848949-92-8 (S)-4-Fluoro-4-methyl-2-pent-4-enoylamino-pentanoic acid ethyl ester 
• 848949-89-3 4-(2-fluoro-2-methyl-propyl)-2-phenyl-4H-oxazol-5-one 
• 156047-39-1 ethyl (2S)-2-amino-4-fluoro-4-methylpentanoate 
• 15722-67-5 3-amino-5,5-dimethyltetrahydro-2-furanone (hydrochloride) 

Relevant academic research and scientific papers

INHIBITING HUMAN INTEGRIN α4β7

Disclosed are small molecule antagonists of human α4β7 integrin, and methods of using them to treat a number of diseases and conditions.

BICYCLIC HETEROARYL AMIDES AS CATHEPSIN CYSTEINE PROTEASE INHIBITORS

The present invention relates to substituted bicyclic heteroaryl amide derivatives that are inhibitors of cathepsin K proteases and which are therefore useful in the treatment of certain disorders that can be prevented or treated by inhibition of these enzymes. In addition, the invention relates to the compounds, methods for their preparation, pharmaceutical compositions containing the compounds and the uses of these compounds in the treatment of certain disorders. It is expected that the compounds of the invention will find application in the treatment of bone diseases such as osteoporosis and osteoarthritis as well as other diseases and conditions. The compounds have the general formula: [Formula should be inserted here]

An efficient chemoenzymatic approach to (S)-γ-fluoroleucine ethyl ester

(Chemical Equation Presented) An asymmetric synthesis of (S)-γ-fluoroleucine ethyl ester 1 is described. The key transformation involves a lipase-catalyzed dynamic ring-opening of 2-(3-butenyl)azlactone 7b with EtOH to give amide ester (S)-6b in 84% enant

Process for preparing fluoroleucine alkyl esters

This invention relates to a stereoselective preparation of fluoroleucine alkyl esters.