851590-15-3Relevant articles and documents
4-(Anilino)pyrrole-2-carboxamides: Novel non-steroidal/non-anilide type androgen antagonists effective upon human prostate tumor LNCaP cells with mutated nuclear androgen receptor
Wakabayashi, Ken-ichi,Imai, Keisuke,Miyachi, Hiroyuki,Hashimoto, Yuichi,Tanatani, Aya
, p. 6799 - 6812 (2008/12/22)
Various 4-(anilino)pyrrole-2-carboxamides were designed and synthesized as novel androgen receptor (AR) antagonists without steroidal or anilide structure, based on our strategy for developing full antagonists of nuclear receptors. Introduction of a bulky