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851684-46-3

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851684-46-3 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 851684-46-3 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 8,5,1,6,8 and 4 respectively; the second part has 2 digits, 4 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 851684-46:
(8*8)+(7*5)+(6*1)+(5*6)+(4*8)+(3*4)+(2*4)+(1*6)=193
193 % 10 = 3
So 851684-46-3 is a valid CAS Registry Number.

851684-46-3SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 19, 2017

Revision Date: Aug 19, 2017

1.Identification

1.1 GHS Product identifier

Product name N-(3-chloro-4-((3-fluorobenzyl)oxy)phenyl)-6-iodoquinazolin-4-amine hydrochloride

1.2 Other means of identification

Product number -
Other names N-(3-Chloro-4-(3-fluorobenzyloxy)phenyl)-6-iodoquinazolin-4-amine drochloride

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:851684-46-3 SDS

851684-46-3Relevant articles and documents

Kinase scaffold repurposing for neglected disease drug discovery: Discovery of an efficacious, lapatanib-derived lead compound for trypanosomiasis

Patel, Gautam,Karver, Caitlin E.,Behera, Ranjan,Guyett, Paul J.,Sullenberger, Catherine,Edwards, Peter,Roncal, Norma E.,Mensa-Wilmot, Kojo,Pollastri, Michael P.

, p. 3820 - 3832 (2013/06/27)

Human African trypanosomiasis (HAT) is a neglected tropical disease caused by the protozoan parasite Trypanosoma brucei. Because drugs in use against HAT are toxic and require intravenous dosing, new drugs are needed. Initiating lead discovery campaigns b

QUINAZOLINE DERIVATIVE HAVING TYROSINE KINASE INHIBITORY ACTIVITY

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Page/Page column 62-63, (2008/06/13)

A compound represented by the general formula (I) or a pharmaceutically acceptable salt thereof or a solvate of the compound or the salt: (I) wherein Rx represents a group represented by the formula(II): where R1 represents a hydrogen atom, an alkyl group which may be substituted or the like, Z represents -O-, -N(R10)- or the like, R10 represents a hydrogen atom, an alkyl group or the like, R2 represents a hydrogen atom, an alkyl group which may be substituted or the like, R18 represents a hydrogen atom, an alkyl group which may be substituted or the like, R19 represents an alkyl group which may be substituted or the like, W1 represents a non-aromatic nitrogenated heterocyclic group which may be substituted, and R17 represents a hydrogen atom, an alkyl group which may be substituted or the like; R3 and R4 independently represent a hydrogen atom, an alkyl group which may be substituted or the like; X represents -O-, -S-, -N(R12)- or the like; R12 represents a hydrogen atom, an alkyl group or the like; and A represents a phenyl group which may be substituted or the like. The compound can inhibit both EGF receptor tyrosine kinase and HER2 tyrosine kinase.

CYANOGUANIDINES AND CYANOAMIDINES AS ERBB2 AND EGFR INHIBITORS

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Page 21, (2008/06/13)

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