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methyl 6-[({3-{[(1S)-1-methyl-2-(methyloxy)ethyl]oxy}-5-[(phenylmethyl)oxy]phenyl}carbonyl)amino]pyridine-3-carboxylate is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

851885-40-0

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851885-40-0 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 851885-40-0 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 8,5,1,8,8 and 5 respectively; the second part has 2 digits, 4 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 851885-40:
(8*8)+(7*5)+(6*1)+(5*8)+(4*8)+(3*5)+(2*4)+(1*0)=200
200 % 10 = 0
So 851885-40-0 is a valid CAS Registry Number.

851885-40-0Relevant academic research and scientific papers

Design of a potent, soluble glucokinase activator with increased pharmacokinetic half-life

Pike, Kurt G.,Allen, Joanne V.,Caulkett, Peter W.R.,Clarke, David S.,Donald, Craig S.,Fenwick, Mark L.,Johnson, Keith M.,Johnstone, Craig,McKerrecher, Darren,Rayner, John W.,Walker, Rolf P.,Wilson, Ingrid

, p. 3467 - 3470 (2011/06/24)

The continued optimization of a series of glucokinase activators is described, including attempts to understand the interplay between molecular structure and the composite parameter of unbound clearance. These studies resulted in the discovery of a new sc

BENZOYL AMINO PYRIDYL CARBOXYLIC ACID DERIVATIVES USEFUL AS GLUCOKINASE (GLK) ACTIVATORS

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Page/Page column 25-26, (2010/02/12)

Compounds of Formula: (I); wherein: R1 is selected from: fluoro, chloro, C1-3alkyl and C1-3alkoxy; R2-X- is selected from: methyl, methoxymethyl and Formula: (X); n is 0,1 or 2; or a salt, pro-drug or solvate thereof are described. Their use as GLK activators, pharmaceutical compositions containing them, and processes for their preparation are also described.

BENZOYL AMINO PYRIDYL CARBOXYLIC ACID DERIVATIVES USEFUL AS GLUCOKINASE (GLK) ACTIVATORS

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Page/Page column 24-25, (2008/06/13)

A compound of Formula (I): Formula (I) wherein: R1 is selected from hydrogen and C1-4alkyl; R2 is selected from: R4-C(R5aR5b)- , R4=C(R6)- and R7aC(R7b

BENZOYL AMINO PYRIDIL CARBOXYLIC ACID DERIVATIVES AS GLUOKINASE ACTIVATORS

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Page/Page column 24-25, (2008/06/13)

Compounds of Formula (I) wherein: R1-X- is selected from: methyl, methoxymethyl and Formula (X); R2 is selected from hydrogen, methyl, chloro and fluoro; n is 1 or 2; or a salt, pro-drug or solvate thereof, are described. Their use a

PYRIDINE CARBOXYLIC ACID DERIVATIVES AS GLUCOKINASE MODULATORS

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Page/Page column 35-36, (2010/02/11)

A compound of Formula (I): wherein: A is phenyl or a 5- or 6-membered heteroaryl ring, optionally substituted; R1 and R2 are selected from hydrogen and methyl; with the proviso that at least one of R1 and R2 is

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