852227-95-3 Usage
General Description
3-Morpholinophenylboronic acid pinacol ester is a boronic acid derivative with a morpholine group and a pinacol ester functionality. It is commonly used as a reagent in organic synthesis for the formation of carbon-carbon and carbon-heteroatom bonds. 3-MORPHOLINOPHENYLBORONIC ACID PINACOL ESTER has been studied for its potential as a building block in the synthesis of pharmaceuticals and agrochemicals. It is also utilized in the development of medicinal chemistry by serving as a precursor to bioactive molecules and potential drug candidates. Additionally, 3-Morpholinophenylboronic acid pinacol ester has been investigated for its role in catalysis and as a fluoroionophore for the detection of fluoride ions in biological and environmental samples.
Check Digit Verification of cas no
The CAS Registry Mumber 852227-95-3 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 8,5,2,2,2 and 7 respectively; the second part has 2 digits, 9 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 852227-95:
(8*8)+(7*5)+(6*2)+(5*2)+(4*2)+(3*7)+(2*9)+(1*5)=173
173 % 10 = 3
So 852227-95-3 is a valid CAS Registry Number.
InChI:InChI=1/C16H24BNO3/c1-15(2)16(3,4)21-17(20-15)13-6-5-7-14(12-13)18-8-10-19-11-9-18/h5-7,12H,8-11H2,1-4H3
852227-95-3Relevant articles and documents
Nickel-Catalyzed Ipso-Borylation of Silyloxyarenes via C-O Bond Activation
Pein, Wesley L.,Wiensch, Eric M.,Montgomery, John
supporting information, (2021/06/28)
The conversion of silyloxyarenes to boronic acid pinacol esters via nickel catalysis is described. In contrast to other borylation protocols of inert C-O bonds, the method is competent in activating the carbon-oxygen bond of silyloxyarenes in isolated aromatic systems lacking a directing group. The catalytic functionalization of benzyl silyl ethers was also achieved under these conditions. Sequential cross-coupling reactions were achieved by leveraging the orthogonal reactivity of silyloxyarenes, which could then be functionalized subsequently.
SUBSTITUTED PYRIDOPYRAZINES AS NOVEL SYK INHIBITORS
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Paragraph 0173; 0174, (2014/05/08)
Provided are pyridopyrazine compounds of formula (1), pharmaceutical compositions thereof and methods of use therefore, wherein R1, R2, R3, R4 and m are as defined in the specification.
SUBSTITUTED PYRIDOPYRAZINES AS NOVEL SYK INHIBITORS
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Page/Page column 37, (2013/02/27)
Provided are certain pyridopyrazine compounds, pharmaceutical compositions thereof and methods of use therefor.
