852287-07-1Relevant academic research and scientific papers
Thiophene containing triarylmethanes as antitubercular agents
Parai, Maloy Kumar,Panda, Gautam,Chaturvedi, Vinita,Manju,Sinha, Sudhir
, p. 289 - 292 (2008/09/18)
A new series of thiophene containing triarylmethane derivatives were synthesized from the Friedel-Crafts alkylation of diarylcarbinols followed by incorporation of amino alkyl chains. These were evaluated against Mycobacterium tuberculosis H37Rv and showed the activity in the range of 3.12-12.5 μg/mL in vitro.
An easy access to unsymmetric trisubstituted methane derivatives (TRSMs)
Kumar Das, Sajal,Shagufta,Panda, Gautam
, p. 3097 - 3102 (2007/10/03)
A new series of unsymmetric trisubstituted methane derivatives (TRSMs) has been synthesized through Friedel-Crafts alkylation of aromatic nucleophiles using acid-sensitive heteroaryl carbinols.
