852926-47-7Relevant academic research and scientific papers
A mild and efficient procedure for the N-functionalization of S-perfluoroalkylated aryl sulfoximines
Mace, Yohan,Constant-Urban, Celine,Bouvet, Sebastien,Pegot, Bruce,Bournaud, Chloee,Toffano, Martial,Vo-Thanh, Giang,Diter, Patrick,Magnier, Emmanuel
, p. 1505 - 1512 (2013/07/05)
N-Acylated perfluoroalkylated sulfoximines are synthesized easily from the corresponding free NH-sulfoximines on reaction with acid chlorides. This mild procedure is extended to diacid chlorides for the preparation of dimeric N-bridged sulfoximines and to reactions with chloroformates, carbamoyl chlorides, chlorothio-noformates and thiocarbamoyl chlorides as electrophiles. Georg Thieme Verlag Stuttgart New York.
Synthesis of CF3-substituted sulfoximines from sulfonimidoyl fluorides
Kowalczyk, Rafal,Edmunds, Andrew J. F.,Hall, Roger G.,Bolm, Carsten
, p. 768 - 771 (2011/04/24)
N-Protected trifluoromethyl-substituted sulfoximines have been prepared by treatment of sulfonimidoyl fluorides with a combination of the Ruppert-Prakash reagent (TMSCF3) and tetrabutyl ammonium fluoride (TBAF). The starting materials were accessed following two synthetic routes, and for each reaction sequence the substrate scope was evaluated. Accordingly, a wide variety of aryl-substituted products were obtained in moderate to good yield.
