852997-59-2

Upstream product

• 101630-94-8 N,N'-2,6-pyridinediylbis<2,2-dimethylpropanamide> 
• 18063-02-0 2,6-difluorobenzoylchloride 

Downstream Products

• 852997-75-2 4-[[6-amino-5-(2,6-difluorobenzoyl)-2-pyridinyl]amino]-N,N-bis(phenylmethyl)benzenesulfonamide 
• 852997-81-0 [2-amino-6-[(4-nitrophenyl)amino]-3-pyridinyl](2,6-difluorophenyl)methanone 
• 852997-79-6 4-[[6-amino-5-(2,6-difluorobenzoyl)-2-pyridinyl]amino]benzonitrile 
• 852997-87-6 [2-amino-6-[(2-nitrophenyl)amino]-3-pyridinyl](2,6-difluorophenyl)methanone 
• 852997-97-8 [2-amino-6-[(4-aminophenyl)amino]-3-pyridinyl](2,6-difluorophenyl) 
• 852998-01-7 [2-amino-6-[(2-aminophenyl)amino]-3-pyridinyl](2,6-difluorophenyl)methanone 
• 852997-62-7 (2,6-diamino-3-pyridinyl)(2,6-difluorophenyl)methanone 

Relevant academic research and scientific papers

3-Acyl-2,6-diaminopyridines as cyclin-dependent kinase inhibitors: Synthesis and biological evaluation

A novel series of 2,6-diamino-3-acylpyridines were designed and synthesized as cyclin-dependent kinase (CDK) inhibitors. The representative compounds 2r and 11 showed potent CDK1 and CDK2 inhibitory activities and inhibited cellular proliferation in HeLa,

AMINO SUBSTITUTED PYRIDINYL METHANONE COMPOUNDS USEFUL IN TREATING KINASE DISORDERS

The present invention provides amino substituted pyridinyl methanone compounds; pharmaceutical compositions comprising the compounds and methods of synthesis thereof. The compounds, which are cyclin dependent kinase (CDK) inhibitors, can be used to treat