4023-86-3Relevant academic research and scientific papers
Gold Catalysis of Non-Conjugated Haloacetylenes
Siera, Hannah,Semleit, Nina,Kreuzahler, Mathis,W?lper, Christoph,Haberhauer, Gebhard
, p. 1457 - 1470 (2020/12/09)
Gold-catalyzed reactions of conjugated haloacetylenes are well known and usually result in the formation of addition or dimerization products. Herein, we report a gold-catalyzed reaction of non-conjugated haloacetylenes, which leads exclusively to the hal
Catalytic regioselective synthesis of structurally diverse indene derivatives from N-benzylic sulfonamides and disubstituted alkynes
Liu, Cong-Rong,Yang, Fu-Lai,Jin, Yi-Zhou,Ma, Xian-Tao,Cheng, Dao-Juan,Li, Nan,Tian, Shi-Kai
supporting information; experimental part, p. 3832 - 3835 (2010/11/17)
An unprecedented protocol has been developed for the regioselective synthesis of structurally diverse indene derivatives from readily accessible N-benzylic sulfonamides and disubstituted alkynes through FeCl 3-catalyzed cleavage of sp3 carbon-nitrogen bonds to generate benzyl cation intermediates. In the presence of 10 mol % of FeCl 3, a broad range of N-benzylic sulfonamides smoothly react with internal alkynes, alkynylcarbonyl compounds, alkynyl chalcogenides, or alkynyl halides to afford various functionalized indene derivatives with extremely high regioselectivity.
