853058-46-5

Upstream product

• 853058-44-3 4-chloro-5H-pyrrolo[3,2-d]pyrimidine-7-carbonyl chloride 
• 13754-38-6 N-Benzoylpiperazine 
• 77278-38-7 4-benzoylpiperazine-1-carboxylic acid tert-butyl ester 
• 98-88-4 benzoyl chloride 
• 853058-40-9 diethyl 3-amino-1H-2,4-pyrroledicarboxylate 
• 474010-69-0 N-benzoyl-N'-cyanomethylpiperazine 

Downstream Products

• 853058-71-6 1-(4-Benzoylpiperazin-1-yl)-2-(4-(pyridin-3-yl)-5H-pyrrolo[3,2-d]pyrimidin-7-yl)ethane-1,2-dione 
• 1416163-54-6 C₂₅H₂₈N₆O₃ 

Relevant academic research and scientific papers

Inhibitors of HIV-1 attachment. Part 11: The discovery and structure-activity relationships associated with 4,6-diazaindole cores

A series of HIV-1 attachment inhibitors containing a 4,6-diazaindole core were examined in an effort to identify a compound which improved upon the potency and oral exposure of BMS-488043 (2). BMS-488043 (2) is a 6-azaindole-based HIV-1 attachment inhibit

Diazaindole-dicarbonyl-piperazinyl antiviral agents

The invention comprises substituted diazaindole-dicarbonyl-piperazinyl derivatives of general Formula I wherein: Q is selected from the group consisting of — may represent a bond; T is —C(O)— or —CH(CN)—; and —Y— is selected from the group consisting of compositions thereof and their use for treating HIV infection.