77278-38-7

Basic information

• Product Name: 1-Piperazinecarboxylic acid, 4-benzoyl-, 1,1-diMethylethyl ester
• Synonyms: 1-Piperazinecarboxylic acid, 4-benzoyl-, 1,1-diMethylethyl ester;1-Piperazinecarboxylic acid, 4-benzoyl-, 1,1-diMethylethyl ester-2;tert-butyl 4-benzoylpiperazine-1-carboxylate
• CAS NO: 77278-38-7
• Molecular Formula: C₁₆H₂₂N₂O₃
• Molecular Weight: 290.35748
• Mol File: 77278-38-7.mol
• Article Data: 36

Chemical Properties

• Boiling Point: 422.7±38.0 °C(Predicted)
• Appearance: /
• Density: 1.148±0.06 g/cm3(Predicted)
• PKA: 0.10±0.70(Predicted)
• CAS DataBase Reference: 1-Piperazinecarboxylic acid, 4-benzoyl-, 1,1-diMethylethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 1-Piperazinecarboxylic acid, 4-benzoyl-, 1,1-diMethylethyl ester(77278-38-7)
• EPA Substance Registry System: 1-Piperazinecarboxylic acid, 4-benzoyl-, 1,1-diMethylethyl ester(77278-38-7)

Safety Data

• Hazardous Substances Data: 77278-38-7(Hazardous Substances Data)

Usage

Explanation

Different sources of media describe the Explanation of 77278-38-7 differently. You can refer to the following data:
1. This is the formal name of the chemical compound, which describes its structure and composition.
2. The common name for the compound, which is often used in scientific literature and research.
3. The molecular structure of Boc-piperazine consists of a five-membered nitrogen-containing ring (piperazine) with a benzoyl group attached to the 4-position and a 1,1-dimethylethyl ester group.
4. Derivative of piperazinecarboxylic acid
4. Boc-piperazine is derived from piperazinecarboxylic acid, which is a basic structure in organic chemistry.
5. Use as a protecting group for amines
5. Boc-piperazine is often used in organic synthesis to protect amine groups from unwanted reactions, allowing for selective modification of other functional groups in a molecule.
6. Building block for pharmaceuticals and biologically active compounds
6. The 4-benzoyl substituent on the piperazine ring makes Boc-piperazine a useful building block for the synthesis of various pharmaceuticals and compounds with biological activity.
7. Use as a protecting group for carboxylic acids
7. The 1,1-dimethylethyl ester functionality in Boc-piperazine is commonly used to protect carboxylic acids from unwanted reactions during organic synthesis.
8. Importance in pharmaceutical and organic chemistry
8. Boc-piperazine is an important and versatile chemical in the field of pharmaceutical and organic chemistry due to its ability to act as a protecting group and its utility in the synthesis of various compounds.

Molecular structure

A piperazine ring with a 4-benzoyl substituent and a 1,1-dimethylethyl ester group

Upstream product

• 57260-71-6 1-t-Butoxycarbonylpiperazine 
• 100-51-6 benzyl alcohol 
• 81912-53-0 4(S)-(methoxycarbonyl)-N-benzoyl-1,3-oxazolidine-2-thione 
• 81925-64-6 methyl 3-benzoyl-2-thioxothiazolidine-4-carboxylate 
• 93-89-0 benzoic acid ethyl ester 
• 98-88-4 benzoyl chloride 
• 77278-40-1 tert-butyl 4-(benzoyloxy)piperazine-1-carboxylate 
• 611-73-4 Benzoylformic acid 
• 24424-99-5 di-tert-butyl dicarbonate 
• 2902-69-4 2,2,2-trichloroacetophenone 
• 100-52-7 benzaldehyde 
• 65-85-0 benzoic acid 
• 110-85-0 piperazine 

Downstream Products

• 1260098-35-8 2-(4-benzoyl-piperazin-1-yl)-1-{4-[3-((R)-2-methyl-pyrrolidin-1-yl)-propoxy]-phenyl}-ethanone 
• 1622867-07-5 C₂₅H₂₂N₄O₃S 
• 56227-57-7 (4-(2-chloroethyl)piperazin-1-yl)(phenyl)methanone 
• 56227-56-6 (4-(2-hydroxyethyl)piperazin-1-yl)(phenyl)methanone 
• 1071516-65-8 4-benzoylpiperazine-1-carbothioic acid (4-tert-butylphenyl)amide 
• 178312-68-0 [4-(azetidin-3-yl)piperazin-1-yl]phenylmethanone 
• 178312-24-8 3-(4-benzoylpiperazin-1-yl)azetidine-1-carboxylic acid tert-butyl ester 
• 16466-44-7 N-ethyl-N-phenylbenzamide 
• 93-98-1 N-phenyl benzoyl amide 
• 582-78-5 N-(4-methylphenyl)benzamide 
• 937808-26-9 tert-butyl 4-(1,2-diphenylethyl)piperazine-1-carboxylate 
• 444891-21-8 tert-butyl 4-(cyano(phenyl)methyl)piperazine-1-carboxylate 
• 57260-70-5 4-benzyl-piperazine-1-carboxylic acid tert-butyl ester 

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