85370-34-9Relevant academic research and scientific papers
4-Chloro-2-lithio-1-butene, a Novel Donor-Acceptor Conjunctive Reagent
Piers, Edward,Karunaratne, Veranja
, p. 1774 - 1776 (1983)
Transmetalation of 4-chloro-2-(trimethylstannyl)-1-butene (10) provides 4-chloro-2-lithio-1-butene (11), which reacts smoothly at -78 deg C with aldehydes, ketones, and α,β-unsaturated N,N',N'-trimethylhydrazides to produce, after warming of the resultant
ORGANOTIN-BASED BIFUNCTIONAL REAGENTS: 4-CHLORO-2-LITHIO-1-BUTENE AND RELATED SUBSTANCES. METHYLENECYCLOPENTANE ANNULATIONS. TOTAL SYNTHESIS OF (+/-)-Δ9(12)-CAPNELLENE
Piers, Edward,Karunaratne, Veranja
, p. 1089 - 1104 (2007/10/02)
Transmetalation of 4-chloro-2-trimethylstannyl-1-butene (4) with MeLi in tetrahydrofuran (THF) at -78 deg C affords 4-chloro-2-lithio-1-butene (5).At low temperature (below approximately -50 to -60 deg C), 5 functions well as a bifunctional reagent.For ex
