85370-40-7Relevant academic research and scientific papers
An Easy Procedure for the Preparation of 3-Methylidenetetrahydrofurans from Dimethyl Succinates
Corral, Jose M. Miguel,Gordaliza, Marina,Castro, M. Angeles,Salinero, Miguel A.,Dorado, Jose M.,Feliciano, Arturo San
, p. 154 - 164 (2007/10/03)
A new synthetic proceduree to obtain 3-methylidenetetrahydrofurans is described, in which the methylidene group is generated during the formation of the tetrahydrofuran ring. These are prepared by reduction of differently substituted dimethyl succinates obtained by Stobbe condensation.
Regioselective Borohydride and Grignard Reactions in (E)-3-(Arylmethylene)-2-oxotetrahydrofurans
De, Dibyendu,Seth, Manju,Bhaduri, Amiya Prasad
, p. 956 - 959 (2007/10/02)
Convenient syntheses of (E)-2-(arylmethylene)-1,4-butanediols 2a-c, 2-(aryl)-3-methylenetetrahydrofurans 4a,c, 3-(arylmethylene)-2-methyl-2,5-pentanediols 7a-c, 4-(arylmethylene)-3-ethyl-3,6-hexanediols 7d-f, 2,2-dialkyl-3-(arylmethylene)tetrahydrofurans
ORGANOTIN-BASED BIFUNCTIONAL REAGENTS: 4-CHLORO-2-LITHIO-1-BUTENE AND RELATED SUBSTANCES. METHYLENECYCLOPENTANE ANNULATIONS. TOTAL SYNTHESIS OF (+/-)-Δ9(12)-CAPNELLENE
Piers, Edward,Karunaratne, Veranja
, p. 1089 - 1104 (2007/10/02)
Transmetalation of 4-chloro-2-trimethylstannyl-1-butene (4) with MeLi in tetrahydrofuran (THF) at -78 deg C affords 4-chloro-2-lithio-1-butene (5).At low temperature (below approximately -50 to -60 deg C), 5 functions well as a bifunctional reagent.For ex
4-Chloro-2-lithio-1-butene, a Novel Donor-Acceptor Conjunctive Reagent
Piers, Edward,Karunaratne, Veranja
, p. 1774 - 1776 (2007/10/02)
Transmetalation of 4-chloro-2-(trimethylstannyl)-1-butene (10) provides 4-chloro-2-lithio-1-butene (11), which reacts smoothly at -78 deg C with aldehydes, ketones, and α,β-unsaturated N,N',N'-trimethylhydrazides to produce, after warming of the resultant
