85458-76-0

Upstream product

• 6347-01-9 fructopyranose 
• 25018-67-1 1,2;4,5-di-O-isopropylidene-β-D-(-)-fructopyranose 
• 100-44-7 benzyl chloride 
• 100-39-0 benzyl bromide 

Downstream Products

• 801289-08-7 (5R,8R,9R,10S)-1-aza-10-benzyloxy-8,9-dimethylmethylenedioxy-2-methyl-3,6-dioxaspiro[4.5]dec-1-ene 
• 364635-35-8 ((3aR,6R,7S,7aR)-6-Azido-7-benzyloxy-2,2-dimethyl-tetrahydro-[1,3]dioxolo[4,5-c]pyran-6-ylmethoxy)-trimethyl-silane 
• 118020-54-5 O³-benzyl-D-arabino-[2]hexosulose-bis-phenylhydrazone 
• 109445-40-1 O³-benzyl-2-hydroxymethyl-D-arabino-hexitol 
• 906330-56-1 O³-benzyl-2-hydroxymethyl-D-mannonic acid-4-lactone 
• 1245436-45-6 5-azido-3-O-benzyl-5-deoxy-1,2-O-isopropylidene-β-D-fructopyranose 
• 927809-66-3 5-azido-4-O-benzoyl-3-O-benzyl-5-deoxy-1,2,-O-isopropylidene-β-D-fructopyranose 
• 927809-65-2 4-O-benzoyl-3-O-benzyl-5-deoxy-5-iodo-1,2-O-isopropylidene-α-L-sorbopyranose 
• 927809-64-1 4-O-benzoyl-3-O-benzyl-1,2-O-isopropylidene-β-D-fructopyranose 
• 141564-96-7 (2S,3R,4R,5R)-4-Benzyloxy-2-fluoro-hexane-1,3,5-triol 
• 141564-96-7 (2S,3R,4R,5S)-4-Benzyloxy-2-fluoro-hexane-1,3,5-triol 
• 141564-89-8 (5S,8R,9R,10S)-10-Benzyloxy-9-(tert-butyl-dimethyl-silanyloxy)-2,2-dimethyl-1,3,6-trioxa-spiro[4.5]decan-8-ol 
• 141564-90-1 3-O-benzyl-4-O-tert-butyldimethylsilyl-5-deoxy-5-fluoro-1,2-O-isopropylidene-α-L-sorbopyranose 
• 141564-93-4 (2S,3S,5S)-3-Benzyloxy-2-bromomethyl-5-fluoro-2-methoxy-tetrahydro-pyran-4-one 

Relevant academic research and scientific papers

Synthesis of a poly-hydroxypyrolidine-based inhibitor of Mycobacterium tuberculosis GlgE

(Chemical Equation Presented). Long treatment times, poor drug compliance, and natural selection during treatment of Mycobacterium tuberculosis (Mtb) have given rise to extensively drug-resistant tuberculosis (XDR-TB). As a result, there is a need to iden

Aromatic or chiral heterocycle - Balance between 1,3-oxazoline-2-thione and 1,3-oxazolidine-2-thione

1,3-Oxazoline-2-thiones (OXT) and bis-1,3-oxazol-idine-2-thiones (bis-OZT) were selectively prepared depending on the conditions and starting materials used, and then underwent some N- and S-selective reactions. Georg Thieme Verlag Stuttgart.

Selective formation of 1,3-oxazolidine-2-thiones on ketohexose templates

Thiocyanic acid condensation on selectively protected ketohexose led to the isolation of five out of the seven possible 1,3-oxazolidine-2-thiones (OZT). The four isomeric spiro-OZT synthesized showed promising biological activity against D-fructose transp

Asymmetric Cyclopropanation Using New Chiral Auxiliaries Derived from D-Fructose

Acetals of α,β-unsaturated aldehydes with 3-O-alkylated derivatives of 1,2-O-isopropylidene-β-D-fructopyranose and 1,2-O-isopropylidene-β-D-psicopyranose, which are readily available from D-fructose, were cyclopropanated with Et2Zn and CH2I2 with good diastereoselectivity.The effects of structure of the acetals on enantioselectivity were examined.

A Synthesis of 2,6-Dideoxy-2-fluoro-L-glycopyranose from D-Fructose: Synthesis of 1,3,4-Tri-O-acetyl-2,6-dideoxy-2-fluoro-L-talopyranose

2,6-Dideoxy-2-fluoro-α-L-talopyranose has been prepared as its triacetate from inexpensive D-fructose by head-to-tail inversion.

ALKYLATION OF CARBOHYDRATES IN A CATALYTIC TWO-PHASE SYSTEM

Alkylation of hydroxyl groups of sugars has been performed by means of primary alkyl halides or sulfates in a catalytic two-phase (CTP) system containing a concentrated, aqueous sodium hydroxide solution and a catalyst, i.e. tetra-n-butylammonium chloride.The corresponding ethers were formed with a very high yield.