85593-60-8Relevant academic research and scientific papers
SIMPLE EFFICIENT SYNTHESIS OF LTB4 AND 12-epi-LTB4
Zamboni, Robert,Rokach, Joshua
, p. 2631 - 2634 (1982)
Using L- and D-arabinose respectively as the source of chirality at C-12 in LTB4, efficient new syntheses of LTB4 and 12-epi-LTB4 have been realized.
TOTAL SYNTHESIS OF LIPOXIN B: ASSIGNMENT OF STEREOCHEMISTRY
Leblanc, Yves,Fitzsimmons, Brian,Adams, Julian,Rokach, Joshua
, p. 1399 - 1402 (2007/10/02)
Four isomers of lipoxin B were synthesized using carbohydrate precursors.An authentic sample of lipoxin B (from human leukocytes) was found to be a mixture of all-trans isomers 1a and 1c.
STEREOSPECIFIC SYNTHESIS OF TWO METABOLITES OF LTB4
Zamboni, Robert,Rokach, Joshua
, p. 4751 - 4754 (2007/10/02)
The stereospecific synthesis of the recently identified metabolites of LTB4 1: 5(S),12(R),20-trihydroxy-6-cis,8,10-trans,14-cis-eicosatetraenoic acid 2 and 5(S),12(R),dihydroxy-6-cis,8,10-trans,14-cis-eicosatetraen-1,20-dioic acid 3, via the synthon 4 has been accomplished; identity of synthetic and natural products has been confirmed.
