85593-60-8

Upstream product

• 83692-41-5 (R)-1-((S)-2,2-Dimethyl-[1,3]dioxolan-4-yl)-3,3-bis-ethylsulfanyl-propan-1-ol 
• 94292-91-8 (S)-1-((S)-2,2-Dimethyl-[1,3]dioxolan-4-yl)-3,3-bis-ethylsulfanyl-propan-1-ol 
• 85593-59-5 tert-Butyl-[(S)-1-((S)-2,2-dimethyl-[1,3]dioxolan-4-yl)-3,3-bis-ethylsulfanyl-propoxy]-diphenyl-silane 
• 85593-59-5 tert-Butyl-[(R)-1-((S)-2,2-dimethyl-[1,3]dioxolan-4-yl)-3,3-bis-ethylsulfanyl-propoxy]-diphenyl-silane 
• 58479-61-1 tert-butylchlorodiphenylsilane 

Downstream Products

• 100311-68-0 tert-Butyl-[(Z)-(R)-1-((S)-2,2-dimethyl-[1,3]dioxolan-4-yl)-non-3-enyloxy]-diphenyl-silane 
• 113426-27-0 (R)-3-(tert-Butyl-diphenyl-silanyloxy)-3-((R)-2,2-dimethyl-[1,3]dioxolan-4-yl)-propionic acid methyl ester 
• 128142-65-4 tert-Butyl-[(S)-1-((S)-2,2-dimethyl-[1,3]dioxolan-4-yl)-hexyloxy]-diphenyl-silane 
• 82493-59-2 Benzoic acid (2Z,4E,6E,10Z)-(1S,8S)-8-(tert-butyl-diphenyl-silanyloxy)-1-(3-ethoxycarbonyl-propyl)-hexadeca-2,4,6,10-tetraenyl ester 
• 82498-75-7 (2E,4E,8Z)-(S)-6-(tert-Butyl-diphenyl-silanyloxy)-tetradeca-2,4,8-trienoic acid ethyl ester 
• 100311-69-1 (Z)-(2S,3R)-3-(tert-Butyl-diphenyl-silanyloxy)-undec-5-ene-1,2-diol 
• 82493-56-9 [(2E,4E,8Z)-(S)-6-(tert-Butyl-diphenyl-silanyloxy)-tetradeca-2,4,8-trienyl]-triphenyl-phosphonium; bromide 
• 100311-74-8 <(tert-butyldiphenylsilyl)oxy>-2(E),6(Z)-decedienal 
• 100428-41-9 2(S)-<(tert-butyldiphenylsilyl)oxy>-4(Z)-decenal 
• 93292-48-9 (Z)-(8R,9S)-8-(tert-Butyl-diphenyl-silanyloxy)-9,10-dihydroxy-dec-5-enoic acid methyl ester 
• 93292-56-9 (5Z,9E,11E)-(R)-8-(tert-Butyl-diphenyl-silanyloxy)-13-hydroxy-trideca-5,9,11-trienoic acid methyl ester 
• 93292-51-4 (5Z,9E)-(R)-8-(tert-Butyl-diphenyl-silanyloxy)-11-oxo-undeca-5,9-dienoic acid methyl ester 
• 93292-50-3 (Z)-(R)-8-(tert-Butyl-diphenyl-silanyloxy)-9-oxo-non-5-enoic acid methyl ester 
• 93292-60-5 [(2E,4E,8Z)-(R)-6-(tert-Butyl-diphenyl-silanyloxy)-12-methoxycarbonyl-dodeca-2,4,8-trienyl]-triphenyl-phosphonium; bromide 

Relevant academic research and scientific papers

SIMPLE EFFICIENT SYNTHESIS OF LTB4 AND 12-epi-LTB4

Using L- and D-arabinose respectively as the source of chirality at C-12 in LTB4, efficient new syntheses of LTB4 and 12-epi-LTB4 have been realized.

TOTAL SYNTHESIS OF LIPOXIN B: ASSIGNMENT OF STEREOCHEMISTRY

Four isomers of lipoxin B were synthesized using carbohydrate precursors.An authentic sample of lipoxin B (from human leukocytes) was found to be a mixture of all-trans isomers 1a and 1c.

STEREOSPECIFIC SYNTHESIS OF TWO METABOLITES OF LTB4

The stereospecific synthesis of the recently identified metabolites of LTB4 1: 5(S),12(R),20-trihydroxy-6-cis,8,10-trans,14-cis-eicosatetraenoic acid 2 and 5(S),12(R),dihydroxy-6-cis,8,10-trans,14-cis-eicosatetraen-1,20-dioic acid 3, via the synthon 4 has been accomplished; identity of synthetic and natural products has been confirmed.