82493-56-9

Basic information

• Product Name: <6(R)-<(tert-butyldiphenylsilyl)oxy>-2(E),4(E),8(Z)-tetradecatrien-1-yl>triphenylphosphonium bromide
• Synonyms: <6(R)-<(tert-butyldiphenylsilyl)oxy>-2(E),4(E),8(Z)-tetradecatrien-1-yl>triphenylphosphonium bromide
• CAS NO: 82493-56-9
• Molecular Weight: 787.935
• Mol File: 82493-56-9.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: <6(R)-<(tert-butyldiphenylsilyl)oxy>-2(E),4(E),8(Z)-tetradecatrien-1-yl>triphenylphosphonium bromide(CAS DataBase Reference)
• NIST Chemistry Reference: <6(R)-<(tert-butyldiphenylsilyl)oxy>-2(E),4(E),8(Z)-tetradecatrien-1-yl>triphenylphosphonium bromide(82493-56-9)
• EPA Substance Registry System: <6(R)-<(tert-butyldiphenylsilyl)oxy>-2(E),4(E),8(Z)-tetradecatrien-1-yl>triphenylphosphonium bromide(82493-56-9)

Safety Data

• Hazardous Substances Data: 82493-56-9(Hazardous Substances Data)

Upstream product

• 101398-98-5 1-bromo-6(R)-<(tert-butyldiphenylsilyl)oxy>-2(E),4(E),8(Z)-tetradecatriene 
• 603-35-0 triphenylphosphine 
• 82498-75-7 ethyl 6(R)-<(tert-butyldiphenylsilyl)oxy>-2(E).4(E),8(Z)-tetradecatrienoate 
• 82493-55-8 6(R)-<(tert-butyldiphenylsilyl)oxy>-2(E),4(E),8(Z)-tetradecatrien-1-ol 
• 100428-42-0 2(R)-<(tert-butyldiphenylsilyl)oxy>dec-4(Z)-enal 
• 100311-75-9 4(R)-<(tert-butyldiphenylsilyl)oxy>dodeca-2(E),6(Z)-dienal 
• 101226-14-6 2-oxodec-4(Z)-enal diethyl acetal 
• 101226-19-1 2(R)-(tert-butyldiphenylsiloxy)dec-4(Z)-enal diethyl acetal 
• 101226-13-5 (Z)-1,1-Diethoxy-dec-4-en-2-ol 
• 101313-13-7 2(R)-hydroxydec-4(Z)-enal diethyl acetal 
• 101226-15-7 2-hydroxydec-4-yn-1-al diethyl acetal 
• 101313-12-6 2(R)-hydroxydec-4-yn-1-al diethyl acetal 
• 101226-18-0 2-acetoxydec-4-yn-1-al diethyl acetal 
• 82498-75-7 (2E,4E,8Z)-(S)-6-(tert-Butyl-diphenyl-silanyloxy)-tetradeca-2,4,8-trienoic acid ethyl ester 

Downstream Products

• 71160-24-2 Leukotriene B 
• 76745-31-8 methyl 5(S)-(benzoyloxy)-12(R)-hydroxy-6(Z),8(E),10(E),14(Z)-eicosatetraenoate 
• 82493-60-5 (5S,12R,6Z,8E,10E,14Z)-ethyl 5-benzoyloxy-12-hydroxyicosatetra-6,8,10,14-enoate 
• 83709-73-3 12-epi-leukotriene B4 
• 70578-51-7 6-trans-Leukotriene B₄ 
• 82493-59-2 Benzoic acid (2Z,4E,6E,10Z)-(1S,8S)-8-(tert-butyl-diphenyl-silanyloxy)-1-(3-ethoxycarbonyl-propyl)-hexadeca-2,4,6,10-tetraenyl ester 
• 119392-39-1 ethyl 6(S)-(benzoyloxy)-13(R)-<(tert-butyldiphenylsilyl)oxy>-7(Z),9(E),11(E),15(Z)-henicosatetraenoate 
• 119413-60-4 ethyl 6(S)-(benzoyloxy)-13(R)-<(tert-butyldiphenylsilyl)oxy>-7(E),9(E),11(E),15(Z)-henicosatetraenoate 
• 82493-59-2 ethyl 5(S)-(benzoyloxy)-12(R)-<(tert-butyldiphenylsilyl)oxy>-6(Z),8(E),10(E),14(Z)-icosatetraenoate 
• 101226-20-4 methyl 5(S)-(benzoyloxy)-12(R)-(tert-butyldiphenylsiloxy)-6(Z),8(E),10(E),14(Z)-eicosatetraenoate 
• 101226-21-5 Benzoic acid (2Z,4E,6E,10E)-(1S,8R)-8-(tert-butyl-diphenyl-silanyloxy)-1-(3-methoxycarbonyl-propyl)-hexadeca-2,4,6,10-tetraenyl ester 
• 82493-61-6 ethyl 5(S)-(benzoyloxy)-12(R)-<(tert-butyldiphenylsilyl)oxy>-6(E),8(E),10(E),14(Z)-icosatetraenoate 

Relevant articles and documents

Total Synthesis of Leukotriene B44> and Homo-LTB4 from D-Mannitol

A convergent total synthesis of leukotriene B4 and its homo analogue has been carried out via enantiomerically pure α-hydroxy aldehydes, chiral key intermediates obtained from D-mannitol and connected at a four carbon atom interval by Wittig re

Total synthesis of leukotriene (+)-LTB4 from D-mannitol

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SIMPLE EFFICIENT SYNTHESIS OF LTB4 AND 12-epi-LTB4

Using L- and D-arabinose respectively as the source of chirality at C-12 in LTB4, efficient new syntheses of LTB4 and 12-epi-LTB4 have been realized.