82498-75-7

Upstream product

• 867-13-0 diethoxyphosphoryl-acetic acid ethyl ester 
• 100311-75-9 4(R)-<(tert-butyldiphenylsilyl)oxy>dodeca-2(E),6(Z)-dienal 
• 688-49-3 ethyl (diethoxyphosphino)acetate 
• 82493-54-7 ethyl 6(R)-hydroxy-2(E),4(E),8(Z)-tetradecatrienoate 
• 58479-61-1 tert-butylchlorodiphenylsilane 
• 628-71-7 1-Heptyne 
• 109420-88-4 9(R),12(R)-bis<(tert-butyldiphenylsilyl)oxy>-6-(Z),14(Z)-icosadiene-10(S),11(S)-diol 
• 109420-87-3 9(R),12(R)-bis<(tert-butyldiphenylsilyl)oxy>-10(S),11(S)-O-(1-methylethylidene)-6(Z),14(Z)-icosadiene-10,11-diol 
• 119414-22-1 9(R),12(R)-bis<(tert-butyldiphenylsilyl)oxy>-10(S),11(S)-O-(1-methylethylidene)-6,14-icosadiyne-10,11-diol 
• 42017-07-2 1-heptynyllithium 
• 16666-79-8 hexylidenetriphenylphosphoran 
• 100333-62-8 (2R,3S)-(Z)-3-O-(tert-butyldiphenylsilyl)-5-undecene-1,2,3-triol 
• 93292-42-3 2-deoxy-3-O-(tert-butyldiphenylsilyl)-4,5-bis-O-(1-methylethylidene)-D-erythro-pentose 
• 93292-41-2 2-deoxy-3-O-(tert-butyldiphenylsilyl)-4,5-O-isopropylidene-D-erythro-pentose diethyl dithioacetal 

Downstream Products

• 82493-56-9 <6(R)-<(tert-butyldiphenylsilyl)oxy>-2(E),4(E),8(Z)-tetradecatrien-1-yl>triphenylphosphonium bromide 
• 71160-24-2 Leukotriene B 
• 101398-98-5 1-bromo-6(R)-<(tert-butyldiphenylsilyl)oxy>-2(E),4(E),8(Z)-tetradecatriene 
• 76745-31-8 methyl 5(S)-(benzoyloxy)-12(R)-hydroxy-6(Z),8(E),10(E),14(Z)-eicosatetraenoate 
• 101226-20-4 methyl 5(S)-(benzoyloxy)-12(R)-(tert-butyldiphenylsiloxy)-6(Z),8(E),10(E),14(Z)-eicosatetraenoate 
• 101226-21-5 Benzoic acid (2Z,4E,6E,10E)-(1S,8R)-8-(tert-butyl-diphenyl-silanyloxy)-1-(3-methoxycarbonyl-propyl)-hexadeca-2,4,6,10-tetraenyl ester 
• 82493-59-2 ethyl 5(S)-(benzoyloxy)-12(R)-<(tert-butyldiphenylsilyl)oxy>-6(Z),8(E),10(E),14(Z)-icosatetraenoate 
• 82493-61-6 ethyl 5(S)-(benzoyloxy)-12(R)-<(tert-butyldiphenylsilyl)oxy>-6(E),8(E),10(E),14(Z)-icosatetraenoate 
• 82493-60-5 (5S,12R,6Z,8E,10E,14Z)-ethyl 5-benzoyloxy-12-hydroxyicosatetra-6,8,10,14-enoate 
• 119392-39-1 ethyl 6(S)-(benzoyloxy)-13(R)-<(tert-butyldiphenylsilyl)oxy>-7(Z),9(E),11(E),15(Z)-henicosatetraenoate 
• 119413-60-4 ethyl 6(S)-(benzoyloxy)-13(R)-<(tert-butyldiphenylsilyl)oxy>-7(E),9(E),11(E),15(Z)-henicosatetraenoate 
• 70578-51-7 6-trans-Leukotriene B₄ 
• 82493-56-9 [(2E,4E,8Z)-(S)-6-(tert-Butyl-diphenyl-silanyloxy)-tetradeca-2,4,8-trienyl]-triphenyl-phosphonium; bromide 
• 83709-73-3 12-epi-leukotriene B4 

Relevant academic research and scientific papers

Total Synthesis of Leukotriene B44> and Homo-LTB4 from D-Mannitol

A convergent total synthesis of leukotriene B4 and its homo analogue has been carried out via enantiomerically pure α-hydroxy aldehydes, chiral key intermediates obtained from D-mannitol and connected at a four carbon atom interval by Wittig re

A Chemoenzymatic Synthesis of Leukotriene B4

A total synthesis of leukotriene B4 (1) is accomplished by the assembly of the key chirons 2 and 3, which are prepared via enzymatic methods.

SIMPLE EFFICIENT SYNTHESIS OF LTB4 AND 12-epi-LTB4

Using L- and D-arabinose respectively as the source of chirality at C-12 in LTB4, efficient new syntheses of LTB4 and 12-epi-LTB4 have been realized.